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马来西亚霹雳州拉律、马当和斯拉马地区麻疹的分析及相关因素

Analysis and Factors Associated with Measles in Larut, Matang and Selama Districts, Perak, Malaysia.

作者信息

Qamruddin Asraf Ahmad, Qamruddin Reza, Malik Ayu

机构信息

Larut Matang and Selama District Health Office, Perak, Malaysia.

Emergency Department, Melaka Hospital, Melaka, Malaysia.

出版信息

Malays J Med Sci. 2020 Oct;27(5):130-140. doi: 10.21315/mjms2020.27.5.13. Epub 2020 Oct 27.

Abstract

OBJECTIVES

To determine the incidence rate of measles and the factors associated with confirmed measles cases in Larut, Matang and Selama districts.

METHODS

Cross-sectional analysis was carried out looking at all suspected and laboratory-confirmed measles cases in Larut, Matang and Selama districts between 2015 and 2019. Multiple logistic regression analysis was used to determine the associated factors for laboratory-confirmed measles cases.

RESULTS

The incidence rate for suspected measles showed an increasing trend from 2015-2019. For laboratory-confirmed measles cases, the incidence rate showed more variation with an increase to 36.11 per million population in 2017 from 5.67 per million population in 2015. The incidence rate later decreased to 10.99 per million population in 2018 and increased again to 24.47 per million population in 2019. From multiple logistic regression analysis, cases that fulfilled the case definition of measles were more likely to be laboratory-confirmed measles. On the other hand, a prior history of measles immunisation was a protective factor.

CONCLUSION

Measles incidence is increasing in trend. Any suspected measles cases that fulfilled the clinical case definitions need to be further investigated. Immunisation should be promoted as they are effective in preventing and eliminating measles.

摘要

目的

确定拉鲁、马当和色拉马地区麻疹的发病率以及与确诊麻疹病例相关的因素。

方法

对2015年至2019年拉鲁、马当和色拉马地区所有疑似和实验室确诊的麻疹病例进行横断面分析。采用多元逻辑回归分析确定实验室确诊麻疹病例的相关因素。

结果

2015年至2019年,疑似麻疹的发病率呈上升趋势。对于实验室确诊的麻疹病例,发病率变化更大,从2015年的每百万人口5.67例增至2017年的每百万人口36.11例。随后发病率在2018年降至每百万人口10.99例,并在2019年再次升至每百万人口24.47例。多元逻辑回归分析显示,符合麻疹病例定义的病例更有可能被实验室确诊为麻疹。另一方面,既往麻疹免疫史是一个保护因素。

结论

麻疹发病率呈上升趋势。任何符合临床病例定义的疑似麻疹病例都需要进一步调查。应推广免疫接种,因为它们对预防和消除麻疹有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3419/7605828/bb31b2e98dac/13mjms27052020_oa10f1.jpg

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