Meyer Tessa, Borgen Patrick, Rojas Kristen
Department of Surgery, Maimonides Medical Center, Brooklyn, NY, USA.
J Surg Case Rep. 2020 Oct 31;2020(10):rjaa399. doi: 10.1093/jscr/rjaa399. eCollection 2020 Oct.
The rarity of male breast cancer continues to limit its study despite increasing incidence rates, particularly within the past decade [Speirs V, Shaaban AM. The rising incidence of male breast cancer. 2009;:429-30]. Although this trend appears to be substantially documented, male patients with breast cancer have been and continue to be excluded from landmark breast cancer trials. Currently, there are no standardized breast cancer screening protocols in place for men, including those with pathogenic BRCA mutations. As a result, men with breast cancer typically present at a later stage, and on average, 8-10 years later than females [Ruddy KJ, Winer EP. Male breast cancer: risk factors, biology, diagnosis, treatment, and survivorship. 2013;:1434-43]. As the incidence of disease continues to rise, the need for algorithmic standardization with regards to screening, diagnosing, treating and managing male breast cancer has become imperative. We report the case of a 71-year-old male who presented with spontaneous bloody nipple discharge and was found to have bilateral ductal carcinoma .
尽管男性乳腺癌的发病率在上升,尤其是在过去十年中[斯皮尔斯V,沙班AM。男性乳腺癌发病率上升。2009年;:429 - 30],但其罕见性仍继续限制着对它的研究。尽管这一趋势似乎有大量文献记载,但男性乳腺癌患者一直且仍然被排除在具有里程碑意义的乳腺癌试验之外。目前,没有针对男性的标准化乳腺癌筛查方案,包括那些携带致病性BRCA突变的男性。因此,男性乳腺癌患者通常在较晚阶段才出现症状,平均而言,比女性晚8 - 10年[鲁迪KJ,维纳EP。男性乳腺癌:风险因素、生物学、诊断、治疗和生存。2013年;:1434 - 43]。随着疾病发病率持续上升,对男性乳腺癌的筛查、诊断、治疗和管理进行算法标准化的需求变得至关重要。我们报告了一例71岁男性病例,该患者出现自发性乳头血性溢液,被发现患有双侧导管癌。