Aiello I, Rosati G, Sau G F, Maioli M, Pacifico A, Traccis S
Neurological Clinic, University of Sassari, Italy.
Eur Neurol. 1987;27(4):251-7. doi: 10.1159/000116165.
Electrophysiological examination was performed on 50 type II diabetic patients to verify whether insulin secretory reserve is a factor influencing the susceptibility to develop polyneuropathy. The results showed that less significant metabolic derangement related to high insulin secretory reserve, and not the high insulin secretory reserve by itself, may prevent the development of neuropathic disorders. These data are consistent with the current opinion that diabetic polyneuropathy is the consequence of the metabolic derangement caused by chronic hyperglycemia.
对50例II型糖尿病患者进行了电生理检查，以验证胰岛素分泌储备是否是影响发生多发性神经病变易感性的一个因素。结果显示，与高胰岛素分泌储备相关的代谢紊乱不太显著，而不是高胰岛素分泌储备本身，可能会阻止神经病变的发展。这些数据与目前认为糖尿病多发性神经病变是慢性高血糖引起的代谢紊乱的结果这一观点一致。
