癌症基因、原癌基因与发育
Cancer genes, proto-oncogenes, and development.
作者信息
Ohlsson R I, Pfeifer-Ohlsson S B
机构信息
Centre for Biotechnology, Karolinska Institute, Huddinge University Hospital, Sweden.
出版信息
Exp Cell Res. 1987 Nov;173(1):1-16. doi: 10.1016/0014-4827(87)90327-2.
PMID:3315703
Abstract
The retroviral cancer genes have in a number of observations been shown to interfere with the developmental program of target cells. Here we are concerned with the interface between cancer genes/proto-oncogenes and developmental processes. Research in this field serves two purposes; to delineate key developmental controls and to identify these as targets for oncogenic agents.
摘要
在许多观察结果中，逆转录病毒致癌基因已被证明会干扰靶细胞的发育程序。在这里，我们关注的是致癌基因/原癌基因与发育过程之间的界面。该领域的研究有两个目的：描绘关键的发育控制机制，并将其确定为致癌因子的作用靶点。
Zotero 插件