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外周静脉穿刺中心静脉置管癌症患者ABO血型与静脉血栓形成风险的关系:一项系统评价和荟萃分析方案

Relationship between ABO blood group and risk of venous thrombosis in cancer patients with peripherally inserted central catheters: A protocol for systematic review and meta-analysis.

作者信息

Liu Fangjing, Zhang Qiang, Rao Li, Song Jifang

机构信息

Department of Oncology, Army Medical Center of PLA, Chongqing, China.

出版信息

Medicine (Baltimore). 2020 Nov 6;99(45):e23091. doi: 10.1097/MD.0000000000023091.

Abstract

BACKGROUND

Peripherally inserted central catheter (PICC) is closely related to venous thromboembolism (VTE). It is a common complication of hospitalized patients, and its etiology is complex. How to prevent the occurrence of VTE is the focus of clinical work. In order to provide basis for individual prevention and accurate treatment of VTE, the purpose of this study was to explore the relationship between ABO blood group and the risk of VTE in cancer patients associated with PICC through meta-analysis.

METHODS

Electronic databases, including Embase, Cochrane Library, Pubmed, Chinese databases SinoMed, Chinese National Knowledge Infrastructure (CNKI), Chinese Scientific Journals Database (VIP), and Wanfang Data, were searched for case-control studies of ABO blood group and PICC-related VTE in cancer patients. The languages were limited to Chinese and English. Two reviewers were responsible for the selection of the study, the extraction of data and the evaluation of the quality of the research. All statistical analyses were carried out with Review Manager 5.3 and Stata 14.0.

RESULTS

The results of this meta-analysis would be published in peer-reviewed journals.

CONCLUSION

This study provided evidence to support the relationship between ABO blood group and the risk of PICC-related VTE in cancer patients.

OSF REGISTRATION NUMBER

DOI 10.17605/OSF.IO/6DPFG.

摘要

背景

经外周静脉穿刺中心静脉置管(PICC)与静脉血栓栓塞症(VTE)密切相关。它是住院患者的常见并发症,其病因复杂。如何预防VTE的发生是临床工作的重点。为了为VTE的个体化预防和精准治疗提供依据,本研究旨在通过荟萃分析探讨ABO血型与癌症患者PICC相关VTE风险之间的关系。

方法

检索电子数据库,包括Embase、Cochrane图书馆、Pubmed、中国数据库中国生物医学文献数据库(SinoMed)、中国知网(CNKI)、维普中文科技期刊数据库(VIP)和万方数据,以查找癌症患者ABO血型与PICC相关VTE的病例对照研究。语言限于中文和英文。两名评审员负责研究的选择、数据提取和研究质量评估。所有统计分析均使用RevMan 5.3和Stata 14.0进行。

结果

本荟萃分析结果将发表在同行评审期刊上。

结论

本研究为支持ABO血型与癌症患者PICC相关VTE风险之间的关系提供了证据。

开放科学框架注册号

DOI 10.17605/OSF.IO/6DPFG。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c9c4/7647597/dc29a871a2d3/medi-99-e23091-g001.jpg

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