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缺血-再灌注干预:从提高运动表现到加速运动恢复——系统评价和荟萃分析。

Ischemia-Reperfusion Intervention: From Enhancements in Exercise Performance to Accelerated Performance Recovery-A Systematic Review and Meta-Analysis.

机构信息

Department of Physiology, Federal University of Juiz de Fora, Juiz de Fora 36036-330, Brazil.

Department of Agrarian Sciences, Federal Institute of Minas Gerais, Bambuí 38900-000, Brazil.

出版信息

Int J Environ Res Public Health. 2020 Nov 4;17(21):8161. doi: 10.3390/ijerph17218161.

DOI:10.3390/ijerph17218161
PMID:33158265
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7672542/
Abstract

It has been demonstrated that brief cycles of ischemia followed by reperfusion (IR) applied before exercise can improve performance and, IR intervention, applied immediately after exercise (post-exercise ischemic conditioning-PEIC) exerts a potential ergogenic effect to accelerate recovery. Thus, the purpose of this systematic review with meta-analysis was to identify the effects of PEIC on exercise performance, recovery and the responses of associated physiological parameters, such as creatine kinase, perceived recovery and muscle soreness, over 24 h after its application. From 3281 studies, six involving 106 subjects fulfilled the inclusion criteria. Compared to sham (cuff administration with low pressure) and control interventions (no cuff administration), PEIC led to faster performance recovery ( = 0.004; ES = -0.49) and lower increase in creatine kinase ( < 0.001; effect size (ES) = -0.74) and muscle soreness ( < 0.001; ES = -0.88) over 24 h. The effectiveness of this intervention is more pronounced in subjects with low/moderate fitness level and at least a total time of 10 min of ischemia (e.g., two cycles of 5 min) is necessary to promote positive effects.

摘要

已经证明,在运动前进行短暂的缺血再灌注(IR)循环可以提高运动表现,而在运动后立即进行的 IR 干预(运动后缺血预处理-PEIC)可以产生潜在的促进恢复效果。因此,本系统评价和荟萃分析的目的是确定 PEIC 在运动后 24 小时内对运动表现、恢复以及相关生理参数(如肌酸激酶、恢复感知和肌肉酸痛)的影响。从 3281 项研究中,有 6 项涉及 106 名受试者符合纳入标准。与假处理(低压袖带)和对照组(不施加袖带)相比,PEIC 可导致更快的运动表现恢复( = 0.004;ES = -0.49)和更低的肌酸激酶增加( < 0.001;ES = -0.74)和肌肉酸痛( < 0.001;ES = -0.88),持续 24 小时。在低/中健身水平的受试者中,这种干预的效果更为明显,并且至少需要 10 分钟的缺血时间(例如,两个 5 分钟的循环)才能产生积极的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e81/7672542/2c9f42932d44/ijerph-17-08161-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e81/7672542/0ccffaded82c/ijerph-17-08161-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e81/7672542/2c9f42932d44/ijerph-17-08161-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e81/7672542/0ccffaded82c/ijerph-17-08161-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e81/7672542/2c9f42932d44/ijerph-17-08161-g002.jpg

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