Department of Radiology, Ege University Faculty of Medicine, Bornova, Izmir, 35100, Turkey.
Department of Gastroenterology, Ege University Faculty of Medicine, Izmir, Turkey.
Jpn J Radiol. 2021 Apr;39(4):341-348. doi: 10.1007/s11604-020-01065-6. Epub 2020 Nov 7.
To assess the use of virtual monochromatic images (VMI) for discrimination of affected and non-affected bowel walls in patients with Crohn's disease (CD) as well as to compare mural enhancement between patients with and without CD.
This retrospective study included 61 patients (47 with CD, 14 without CD). Attenuation value (AV), signal-to noise ratio (SNR), and contrast-to-noise ratio (CNR) were obtained at VMI energy levels from 40 to 110 keV in 10 keV increment. Analyses were performed among affected and non-affected bowel walls in CD patients, as well as from bowel walls in patients without CD. Image quality and mural enhancement were evaluated at VMI energy levels at 40, 70, and 110 keV.
At all energy levels of VMI, each quantitative data for AV, SNR, and CNR showed statistically significant difference between diseased and non-diseased bowel walls in CD patients. In the quantitative assessment of patients with and without CD, the optimal AV and SNR were obtained at 40 keV, and the optimal CNR was obtained at 70 keV. For the qualitative assessment, the best image quality and mural enhancement were obtained at 70 keV and 40 keV, respectively.
VMI are helpful for the differentiation of affected bowel walls in CD patients, providing high diagnostic accuracy.
评估虚拟单能量图像（VMI）在克罗恩病（CD）患者中区分病变和非病变肠壁的应用，并比较有和无 CD 患者之间的壁强化。
本回顾性研究纳入 61 例患者（47 例 CD，14 例无 CD）。在 10 keV 增量的 40 至 110 keV 虚拟单能量水平上，获得衰减值（AV）、信噪比（SNR）和对比噪声比（CNR）。在 CD 患者的病变和非病变肠壁之间以及无 CD 患者的肠壁之间进行分析。在 40、70 和 110 keV 的 VMI 能量水平上评估图像质量和壁强化。
在 VMI 的所有能量水平上，CD 患者的病变和非病变肠壁之间的每个 AV、SNR 和 CNR 的定量数据均有统计学差异。在有和无 CD 的患者的定量评估中，40 keV 时获得最佳的 AV 和 SNR，70 keV 时获得最佳的 CNR。在定性评估中，70 keV 时获得最佳的图像质量，40 keV 时获得最佳的壁强化。
VMI 有助于区分 CD 患者的病变肠壁，提供高诊断准确性。
