• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Single-cell transcriptomics of cardiac progenitors reveals functional subpopulations and their cooperative crosstalk in cardiac repair.

作者信息

Gao Lei, Zhang Hongjie, Cui Jingyi, Pei Lijuan, Huang Shiqi, Mao Yaning, Liu Zhongmin, Wei Ke, Zhu Hongming

机构信息

Translational Medical Center for Stem Cell Therapy, Institute for Regenerative Medicine, Shanghai East Hospital, Tongji University School of Medicine, Shanghai, 200120, China.

Institute for Regenerative Medicine, Shanghai East Hospital, Shanghai Institute of Stem Cell Research and Clinical Translation, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Tongji University, Shanghai, 200092, China.

出版信息

Protein Cell. 2021 Feb;12(2):152-157. doi: 10.1007/s13238-020-00788-6. Epub 2020 Nov 7.

DOI:10.1007/s13238-020-00788-6
PMID:33159668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7862461/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c87f/7862461/50b9e11e0c63/13238_2020_788_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c87f/7862461/866ccc0f15c5/13238_2020_788_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c87f/7862461/50b9e11e0c63/13238_2020_788_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c87f/7862461/866ccc0f15c5/13238_2020_788_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c87f/7862461/50b9e11e0c63/13238_2020_788_Fig2_HTML.jpg

相似文献

1
Single-cell transcriptomics of cardiac progenitors reveals functional subpopulations and their cooperative crosstalk in cardiac repair.心脏祖细胞的单细胞转录组学揭示了功能性亚群及其在心脏修复中的协同串扰。
Protein Cell. 2021 Feb;12(2):152-157. doi: 10.1007/s13238-020-00788-6. Epub 2020 Nov 7.
2
Population and Single-Cell Analysis of Human Cardiogenesis Reveals Unique LGR5 Ventricular Progenitors in Embryonic Outflow Tract.人类心脏发生的群体和单细胞分析揭示了胚胎流出道中独特的 LGR5 心室祖细胞。
Dev Cell. 2019 Feb 25;48(4):475-490.e7. doi: 10.1016/j.devcel.2019.01.005. Epub 2019 Jan 31.
3
Pursuing cardiac progenitors: regeneration redux.追寻心脏祖细胞：再生的回归
Cell. 2005 Feb 11;120(3):295-8. doi: 10.1016/j.cell.2005.01.025.
4
Single-Cell Reconstruction of Progression Trajectory Reveals Intervention Principles in Pathological Cardiac Hypertrophy.单细胞重建进展轨迹揭示病理性心脏肥大的干预原则。
Circulation. 2020 May 26;141(21):1704-1719. doi: 10.1161/CIRCULATIONAHA.119.043053. Epub 2020 Feb 26.
5
Transcriptomic Profiling Maps Anatomically Patterned Subpopulations among Single Embryonic Cardiac Cells.转录组分析绘制单个胚胎心脏细胞中按解剖模式分布的亚群图谱。
Dev Cell. 2016 Nov 21;39(4):491-507. doi: 10.1016/j.devcel.2016.10.014. Epub 2016 Nov 10.
6
Integrin Based Isolation Enables Purification of Murine Lineage Committed Cardiomyocytes.基于整合素的分离方法可实现对小鼠定向分化心肌细胞的纯化。
PLoS One. 2015 Aug 31;10(8):e0135880. doi: 10.1371/journal.pone.0135880. eCollection 2015.
7
TCM visualizes trajectories and cell populations from single cell data.中医从单细胞数据中可视化轨迹和细胞群体。
Nat Commun. 2018 Jul 16;9(1):2749. doi: 10.1038/s41467-018-05112-9.
8
Disturbance of cardiac gene expression and cardiomyocyte structure predisposes Mecp2-null mice to arrhythmias.心脏基因表达和心肌细胞结构的紊乱使Mecp2基因敲除小鼠易患心律失常。
Sci Rep. 2015 Jun 15;5:11204. doi: 10.1038/srep11204.
9
7th Ascona International Workshop on Cardiomyocyte Biology: cardiac pathways of differentiation, metabolism and contraction.第七届阿斯科纳国际心肌细胞生物学研讨会：心脏分化、代谢与收缩途径
Biochim Biophys Acta. 2013 Apr;1833(4):781-2. doi: 10.1016/j.bbamcr.2013.01.002. Epub 2013 Jan 13.
10
Cardiac regeneration: still a 21st century challenge in search for cardiac progenitors from stem cells and embryos.心脏再生：从干细胞和胚胎中寻找心脏祖细胞，这仍然是 21 世纪的挑战。
J Cardiovasc Pharmacol. 2010 Jul;56(1):16-21. doi: 10.1097/FJC.0b013e3181d8bc6d.

引用本文的文献

1
Regulation mechanism of microRNAs in cardiac cells-derived exosomes in cell crosstalk.心脏细胞来源的外泌体中微小RNA在细胞间通讯中的调控机制
Front Pharmacol. 2024 Aug 20;15:1399850. doi: 10.3389/fphar.2024.1399850. eCollection 2024.
2
A division-of-labor mode contributes to the cardioprotective potential of mesenchymal stem/stromal cells in heart failure post myocardial infarction.分工模式有助于骨髓间充质干细胞/基质细胞在心肌梗死后心力衰竭中的心脏保护潜力。
Front Immunol. 2024 Mar 18;15:1363517. doi: 10.3389/fimmu.2024.1363517. eCollection 2024.
3
Wnt3a-Loaded Extracellular Vesicles Promote Alveolar Epithelial Regeneration after Lung Injury.

本文引用的文献

1
Augmenting canonical Wnt signalling in therapeutically inert cells converts them into therapeutically potent exosome factories.增强治疗上无活性细胞中的经典 Wnt 信号转导可将其转化为治疗上有活性的外泌体工厂。
Nat Biomed Eng. 2019 Sep;3(9):695-705. doi: 10.1038/s41551-019-0448-6. Epub 2019 Aug 26.
2
Cardioprotective effect of the secretome of Sca-1+ and Sca-1- cells in heart failure: not equal, but equally important?Sca-1+ 和 Sca-1- 细胞分泌组在心力衰竭中的心脏保护作用：不平等，但同样重要？
Cardiovasc Res. 2020 Mar 1;116(3):566-575. doi: 10.1093/cvr/cvz140.
3
scMCA: A Tool to Define Mouse Cell Types Based on Single-Cell Digital Expression.
Wnt3a 负载的细胞外囊泡促进肺损伤后的肺泡上皮再生。
Adv Sci (Weinh). 2023 Jun;10(18):e2206606. doi: 10.1002/advs.202206606. Epub 2023 Apr 18.
4
Wnt Signaling in Heart Development and Regeneration.Wnt 信号在心脏发育和再生中的作用。
Curr Cardiol Rep. 2022 Oct;24(10):1425-1438. doi: 10.1007/s11886-022-01756-8. Epub 2022 Aug 4.
5
The dynamic facets of the cardiac stroma: from classical markers to omics and translational perspectives.心脏基质的动态方面：从经典标志物到组学及转化医学视角
Am J Transl Res. 2022 Feb 15;14(2):1172-1187. eCollection 2022.
6
Cardiac regeneration following myocardial infarction: the need for regeneration and a review of cardiac stromal cell populations used for transplantation.心肌梗死后的心脏再生：再生的必要性以及用于移植的心脏基质细胞群体综述。
Biochem Soc Trans. 2022 Feb 28;50(1):269-281. doi: 10.1042/BST20210231.
7
is a Potential Biomarker for Radiochemotherapy Sensitivity in Colorectal Cancer.是结直肠癌放化疗敏感性的潜在生物标志物。
Onco Targets Ther. 2021 Mar 2;14:1605-1611. doi: 10.2147/OTT.S296031. eCollection 2021.
scMCA：一种基于单细胞数字表达定义小鼠细胞类型的工具。
Methods Mol Biol. 2019;1935:91-96. doi: 10.1007/978-1-4939-9057-3_6.
4
A Unique Collateral Artery Development Program Promotes Neonatal Heart Regeneration.一种独特的侧支动脉发育方案促进新生儿心脏再生。
Cell. 2019 Feb 21;176(5):1128-1142.e18. doi: 10.1016/j.cell.2018.12.023. Epub 2019 Jan 24.
5
Lack of Cardiac Improvement After Cardiosphere-Derived Cell Transplantation in Aging Mouse Hearts.衰老小鼠心脏中心脏球来源细胞移植后心脏功能无改善。
Circ Res. 2018 Oct 26;123(10):e21-e31. doi: 10.1161/CIRCRESAHA.118.313005.
6
Cell therapy trials for heart regeneration - lessons learned and future directions.心脏再生的细胞治疗临床试验——经验教训和未来方向。
Nat Rev Cardiol. 2018 Nov;15(11):659-671. doi: 10.1038/s41569-018-0013-0.
7
Preclinical Studies of Stem Cell Therapy for Heart Disease.干细胞治疗心脏病的临床前研究。
Circ Res. 2018 Mar 30;122(7):1006-1020. doi: 10.1161/CIRCRESAHA.117.312486.
8
Impact of Cardiac Progenitor Cells on Heart Failure and Survival in Single Ventricle Congenital Heart Disease.心脏祖细胞对单心室先天性心脏病心力衰竭和生存的影响。
Circ Res. 2018 Mar 30;122(7):994-1005. doi: 10.1161/CIRCRESAHA.117.312311. Epub 2018 Jan 24.
9
Single-Cell Transcriptional Profiling Reveals Cellular Diversity and Intercommunication in the Mouse Heart.单细胞转录组谱分析揭示了小鼠心脏中的细胞多样性和相互通讯。
Cell Rep. 2018 Jan 16;22(3):600-610. doi: 10.1016/j.celrep.2017.12.072.
10
Y RNA fragment in extracellular vesicles confers cardioprotection via modulation of IL-10 expression and secretion.细胞外囊泡中的Y RNA片段通过调节白细胞介素-10的表达和分泌赋予心脏保护作用。
EMBO Mol Med. 2017 Mar;9(3):337-352. doi: 10.15252/emmm.201606924.