Department of Psychiatry, Yuzuncu Yil University, Van, Turkey.
Health Services Vocational School, Yuzuncu Yil University, Van, Turkey.
J Pak Med Assoc. 2020 Oct;70(10):1758-1761. doi: 10.5455/JPMA.31213.
To evaluate the association of folate and vitamin B12 levels in patients with conversion disorder, and to illuminate the aetiology of conversion disorder by examining depression and somatoform dissociation.
The case-control study was conducted from March 2014 to May 2015 at the Medical Centre of Yuzuncu Yil University, Van, Turkey, and comprised patients diagnosed with conversion disorder and healthy controls. Blood samples were taken from both groups for vitamin B12 and folate levels. Data was collected using the Beck Depression Inventory and Somatoform Dissociation Scale. Data was analysed using SPSS 18.
Of the 100 subjects, 55(55%) were cases with a mean age of 27.05±9.04 years and 45(45%) were controls with a mean age of 26.56± 5.96 years. The mean level of B12 was 283.93±122.96 in cases and 324.62±128.82 in controls (p=0.05). The mean level of folic acid was 5.47±1.84 in cases and 6.07±2.26 in controls (p>0.05).
Physicians need to be vigilant about vitamin B12 levels in patients with conversion symptoms.
评估转换障碍患者的叶酸和维生素 B12 水平，并通过检查抑郁和躯体分离来阐明转换障碍的病因。
本病例对照研究于 2014 年 3 月至 2015 年 5 月在土耳其凡省于宰云大学医学中心进行，纳入了诊断为转换障碍的患者和健康对照者。两组均采集血样检测维生素 B12 和叶酸水平。采用贝克抑郁量表和躯体分离量表收集数据。采用 SPSS 18 进行数据分析。
在 100 名受试者中，55 名（55%）为病例，平均年龄为 27.05±9.04 岁，45 名（45%）为对照，平均年龄为 26.56±5.96 岁。病例组的 B12 平均水平为 283.93±122.96，对照组为 324.62±128.82（p=0.05）。病例组叶酸的平均水平为 5.47±1.84，对照组为 6.07±2.26（p>0.05）。
医生需要对有转换症状的患者的维生素 B12 水平保持警惕。
