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智利人群中用于神经认知筛查的蒙特利尔认知评估(MoCA)标准化结果。

Standardized results of the Montreal Cognitive Assessment (MoCA) for neurocognitive screening in a Chilean population.

作者信息

Gaete M, Jorquera S, Bello-Lepe S, Mendoza Y M, Véliz M, Alonso-Sanchez M F, Lira J

机构信息

Health Sciences PhD program, Universidad Católica de Murcia, Murcia, España.

Universidad Arturo Prat, Iquique, Chile.

出版信息

Neurologia (Engl Ed). 2020 Nov 5. doi: 10.1016/j.nrl.2020.08.017.

Abstract

INTRODUCTION

Population ageing poses a challenge for countries in preventing and detecting neurodegenerative disorders. The Montreal Cognitive Assessment (MoCA), a short, simple, valid, and reliable screening test, assesses general cognitive status, and is useful in public health contexts. This study aims to normalise and standardise the MoCA test for the Chilean population.

METHOD

We performed a descriptive, correlational validation study of the MoCA test, using a sample including 526 healthy individuals of both sexes, aged between 18 and 90 years, from the north, centre, and south of Chile. We analysed the effects of age, education level, and sex on MoCA performance.

RESULTS

Age and education level had a significant impact on general cognitive performance, as determined by MoCA score. Age, education, and sex account for 1-7% of variance. The mean (standard deviation) score for the total sample was 24.04 (3.22), whereas the normal range originally defined for the instrument is 26-30 points. Older adults with less formal education presented poorer results and lower cognitive performance. We propose a protocol for evaluating results by percentiles and scores for different age ranges, and an individual normalised scalar score.

DISCUSSION

We present normative data for the MoCA test in the Chilean population, and propose cut-off points for different age ranges to discriminate normal cognitive performance from neurocognitive disorders; results are adjusted for education level. This proposal would assist in the use of the test and reduce the rate of false positives.

摘要

引言

人口老龄化给各国预防和检测神经退行性疾病带来了挑战。蒙特利尔认知评估量表(MoCA)是一种简短、简单、有效且可靠的筛查测试,用于评估总体认知状况,在公共卫生环境中很有用。本研究旨在对智利人群的MoCA测试进行标准化和规范化。

方法

我们对MoCA测试进行了描述性、相关性验证研究,使用的样本包括来自智利北部、中部和南部的526名年龄在18至90岁之间的健康男女个体。我们分析了年龄、教育水平和性别对MoCA表现的影响。

结果

年龄和教育水平对由MoCA分数确定的总体认知表现有显著影响。年龄、教育程度和性别占方差的1 - 7%。总样本的平均(标准差)分数为24.04(3.22),而该测试最初定义的正常范围是26 - 30分。受正规教育较少的老年人表现较差,认知能力较低。我们提出了一种通过百分位数和不同年龄范围的分数来评估结果的方案,以及一个个体标准化标量分数。

讨论

我们给出了智利人群MoCA测试的常模数据,并提出了不同年龄范围的截断点,以区分正常认知表现和神经认知障碍;结果根据教育水平进行了调整。这一建议将有助于该测试的使用,并降低假阳性率。

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