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正颌外科中的抗生素应用:回顾性分析及术后感染危险因素的识别。

Antibiotics in orthognathic surgery: a retrospective analysis and identification of risk factors for postoperative infection.

机构信息

Department of Oral and Maxillofacial Surgery, Elisabeth-Tweestedenhospital, Tilburg, The Netherlands.

Department of Oral and Maxillofacial Surgery, Elisabeth-Tweestedenhospital, Tilburg, The Netherlands.

出版信息

Int J Oral Maxillofac Surg. 2021 May;50(5):643-648. doi: 10.1016/j.ijom.2020.09.024. Epub 2020 Nov 5.

DOI:10.1016/j.ijom.2020.09.024
PMID:33162297
Abstract

This study was undertaken to evaluate the infection rate following orthognathic surgery and to identify possible risk factors. A retrospective study was conducted. Patients undergoing orthognathic surgery from August 1, 2017 to July 31, 2018 were included. The outcome variable was surgical site infection (SSI). All data were analysed with respect to demographics and procedure specifications. A total of 137 patients (mean age 28.5±12.69 years) were included in this study, of whom 20 (14.6%) developed a SSI. The only risk factor identified was the type of surgery: those undergoing mandibular osteotomies (in bilateral sagittal split osteotomy (BSSO) or bimaxillary osteotomies) were far more likely to develop infections. Third molar teeth were removed during orthognathic surgery in 28.5% of the procedures, and a genioplasty was performed in 10.9%. Removal of osteosynthesis material because of infectious reasons was necessary in 10.2% of patients, with a strong association to previous SSI. In conclusion, this study showed an infection rate of 14.6% with no link to any demographic risk factor. Neither the simultaneous removal of third molar teeth nor genioplasty was found to be a risk factor for SSI. For literature comparison purposes, there is a clear need for the international guidelines defining SSI to be used.

摘要

本研究旨在评估正颌手术后的感染率,并确定可能的危险因素。这是一项回顾性研究。研究纳入了 2017 年 8 月 1 日至 2018 年 7 月 31 日期间接受正颌手术的患者。手术部位感染(SSI)是本研究的结局变量。所有数据均根据人口统计学和手术规范进行分析。本研究共纳入 137 例患者(平均年龄 28.5±12.69 岁),其中 20 例(14.6%)发生 SSI。唯一确定的危险因素是手术类型:接受下颌骨切开术(双侧矢状劈开截骨术或双颌骨切开术)的患者发生感染的风险更高。在 28.5%的手术中,同时切除了第三磨牙,10.9%进行了颏成形术。由于感染原因,10.2%的患者需要取出内固定材料,这与之前的 SSI 有很强的相关性。总之,本研究显示感染率为 14.6%,与任何人口统计学危险因素无关。同时切除第三磨牙或颏成形术均不是 SSI 的危险因素。为了进行文献比较,明确需要使用国际指南定义 SSI。

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