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新型冠状病毒肺炎疫情期间癌症患者治疗的伦理考量:治还是不治?来自低收入和中等收入国家一家癌症中心的文献综述与观点

Ethical Considerations for Treating Cancer Patients During the SARS-CoV-2 Virus Crisis: To Treat or Not to Treat? A Literature Review and Perspective From a Cancer Center in Low-Middle Income Country.

作者信息

Al-Tabba' Amal, Al-Hussaini Maysa, Mansour Razan, Sultan Hala, Abdel-Razeq Hikmat, Mansour Asem

机构信息

Independent Researcher, Amman, Jordan.

Department of Pathology and Laboratory Medicine, King Hussein Cancer Center, Amman, Jordan.

出版信息

Front Med (Lausanne). 2020 Oct 7;7:561168. doi: 10.3389/fmed.2020.561168. eCollection 2020.

Abstract

Providing routine healthcare to patients with serious health illnesses represents a challenge to healthcare providers amid the SARS-CoV-2 pandemic. Treating cancer patients during this pandemic is even more complex due to their heightened vulnerability, as both cancer and cancer treatment weaken the immune system leading to a higher risk of both infections and severe complications. In addition to the need to protect cancer patients from unnecessary exposure to SARS-CoV-2 infection during their routine care, interruption, and discontinuation of cancer treatment can result in negative consequences on patients' health, in addition to the ghost of rationing healthcare resources in high demand during a global health crisis. This article aims to explore the ethical dilemmas faced by decision-makers and healthcare providers caring for cancer patients during the SARS-CoV-2 pandemic. This includes setting triage criteria for non-infected cancer patients, fairly allocating limited healthcare resources between cancer patients and SARS-CoV-2 patients, prioritizing SARS-CoV-2 treatment or vaccine, once developed, for cancer patients and non-cancer patients, patient-physician communication on matters such as end-of-life and do-not-resuscitate (DNR), and lastly, shifting physicians' priorities from treating their own cancer patients to treating critically ill SARS-CoV-2 infected patients. Ultimately, no straightforward decision can be easily made at such exceptionally difficult times. Applying different ethical principles can result in very different scenarios and consequences. In the end, we will briefly share the experience of the King Hussein Cancer Center (KHCC), the only standalone comprehensive cancer center in the region.

摘要

在新冠疫情期间,为患有严重疾病的患者提供常规医疗服务对医疗服务提供者来说是一项挑战。在这场疫情中治疗癌症患者更为复杂,因为他们的脆弱性更高,癌症和癌症治疗都会削弱免疫系统,导致感染和严重并发症的风险更高。除了在常规护理期间需要保护癌症患者免受不必要的新冠病毒感染外,癌症治疗的中断和停止除了会在全球卫生危机期间医疗资源需求高涨时引发医疗资源配给问题外,还会对患者健康产生负面影响。本文旨在探讨在新冠疫情期间,决策者和照顾癌症患者的医疗服务提供者所面临的伦理困境。这包括为未感染的癌症患者制定分诊标准,在癌症患者和新冠患者之间公平分配有限的医疗资源,一旦研发出新冠治疗方法或疫苗,确定癌症患者和非癌症患者的优先顺序,就临终关怀和不进行心肺复苏(DNR)等问题进行医患沟通,最后,将医生的工作重点从治疗自己的癌症患者转移到治疗重症新冠感染患者。最终,在如此艰难的时期,无法轻易做出简单直接的决定。应用不同的伦理原则可能会导致非常不同的情况和后果。最后,我们将简要分享侯赛因国王癌症中心(KHCC)的经验,该中心是该地区唯一的独立综合性癌症中心。

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