Chang-Xin Liu, Shun-Gang Jiao, Xiao-Chun Zhou, An-Ni L I, Xiao-Jing M A, Sha-Na Wuken, Su-Yi-le Chen, Peng-Fei T U, Xing-Yun Chai
Modern Research Center for Traditional Chinese Medicine, School of Chinese Materia Medica,Beijing University of Chinese Medicine Beijing 100029, China.
Alashan League Mongolian Medicine Hospital Alxa 750300, China.
Zhongguo Zhong Yao Za Zhi. 2020 Sep;45(17):4196-4204. doi: 10.19540/j.cnki.cjcmm.20200608.201.
Syringa pinnatifolia is an endemic species of Syringa in Oleaceae family in China, mainly distributed in Helan Mountain, which is located between Inner Mongolia and Ningxia. Its peeled roots, stems and thick twigs have been used as Mongolian folk medicine, called "Shan-chen-xiang" in Chinese, for the treatment of coronary heart diseases, angina pectoris and other cardiopulmonary diseases. Modern researches showed that S. pinnatifolia mainly contains lignans, sesquiterpenoids, and volatile oils, and displays anti-myocardial ischemia, sedation, analgesia, antibacterial and other effects. In the past five years, many groups have made new progress on the study of chemical constituents and pharmacological activities of S. pinnatifolia. On the basis of the previous review by our group, this paper summarizes the advances which is beneficial to the development, research and clinical application of S. pinnatifolia, particularly Shan-chen-xiang.
羽叶丁香是中国木犀科丁香属的特有物种,主要分布于内蒙古和宁夏之间的贺兰山。其根皮、茎及粗枝被用作蒙药,中文名为“山沉香”,用于治疗冠心病、心绞痛等心肺疾病。现代研究表明,羽叶丁香主要含有木脂素、倍半萜类化合物和挥发油,并具有抗心肌缺血、镇静、镇痛、抗菌等作用。在过去五年中,许多研究团队在羽叶丁香的化学成分和药理活性研究方面取得了新进展。基于本团队之前的综述,本文总结了这些进展,这将有助于羽叶丁香,尤其是山沉香的开发、研究及临床应用。