de Lusignan Simon, Hobbs F D Richard, Liyanage Harshana, Ferreira Filipa, Tripathy Manasa, Munro Neil, Feher Michael, Joy Mark
Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, United Kingdom.
Royal College of General Practitioners Research and Surveillance Centre, London, United Kingdom.
JMIR Res Protoc. 2020 Nov 9;9(11):e21259. doi: 10.2196/21259.
Atrial fibrillation (AF) is one of the commonest arrhythmias observed in general practice. The thromboembolic complications of AF include transient ischemic attack, stroke, and pulmonary embolism. Early recognition of AF can lead to early intervention with managing the risks of these complications.
The primary aim of this study is to investigate if patients are managed in general practice according to current national guidelines. In addition, the study will evaluate the impact of direct oral anticoagulant use with respect to AF complications in a real-world dataset. The secondary aims of the study are to develop a dashboard that will allow monitoring the management of AF in general practice and evaluate the usability of the dashboard.
The study was conducted in 2 phases. The initial phase was a quantitative analysis of routinely collected primary care data from the Oxford Royal College of General Practitioners Research and Surveillance Center (RCGP RSC) sentinel network database. AF cases from 2009 to 2019 were identified. The study investigated the impact of the use of anticoagulants on complications of AF over this time period. We used this dataset to examine how AF was managed in primary care during the last decade. The second phase involved development of an online dashboard for monitoring management of AF in general practice. We conducted a usability evaluation for the dashboard to identify usability issues and performed enhancements to improve usability.
We received funding for both phases in January 2019 and received approval from the RCGP RSC research committee in March 2019. We completed data extraction for phase 1 in May 2019 and completed analysis in December 2019. We completed building the AF dashboard in May 2019. We started recruiting participants for phase 1 in May 2019 and concluded data collection in July 2019. We completed data analysis for phase 2 in October 2019. The results are expected to be published in the second half of 2020. As of October 2020, the publications reporting the results are under review.
Results of this study will provide an insight into the current trends in management of AF using real-world data from the Oxford RCGP RSC database. We anticipate that the outcomes of this study will be used to guide the development and implementation of an audit-based intervention tool to assist practitioners in identifying and managing AF in primary care.
INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): RR1-10.2196/21259.
心房颤动(AF)是全科医疗中最常见的心律失常之一。AF的血栓栓塞并发症包括短暂性脑缺血发作、中风和肺栓塞。早期识别AF可促使早期干预,以控制这些并发症的风险。
本研究的主要目的是调查患者在全科医疗中是否按照当前国家指南进行管理。此外,该研究将在真实世界数据集中评估直接口服抗凝剂的使用对AF并发症的影响。该研究的次要目的是开发一个仪表板,用于监测全科医疗中AF的管理情况,并评估该仪表板的可用性。
该研究分两个阶段进行。初始阶段是对从牛津皇家全科医师学院研究与监测中心(RCGP RSC)哨点网络数据库常规收集的初级保健数据进行定量分析。识别出2009年至2019年的AF病例。该研究调查了在此期间使用抗凝剂对AF并发症的影响。我们使用该数据集来研究过去十年中初级保健中AF是如何管理的。第二阶段涉及开发一个在线仪表板,用于监测全科医疗中AF的管理情况。我们对该仪表板进行了可用性评估,以识别可用性问题,并进行了改进以提高可用性。
我们在2019年1月获得了两个阶段的资金,并于2019年3月获得了RCGP RSC研究委员会的批准。我们于2019年5月完成了第一阶段的数据提取,并于2019年12月完成了分析。我们于2019年5月完成了AF仪表板的构建。我们于2019年5月开始招募第一阶段的参与者,并于2019年7月结束了数据收集。我们于2019年10月完成了第二阶段的数据分析。结果预计将于2020年下半年发表。截至2020年10月,报告结果的出版物正在审核中。
本研究结果将利用牛津RCGP RSC数据库的真实世界数据,深入了解当前AF管理的趋势。我们预计本研究结果将用于指导基于审核的干预工具的开发和实施,以协助从业者在初级保健中识别和管理AF。
国际注册报告识别号(IRRID):RR1-10.2196/21259。