• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

原发性侧索硬化症表现类似帕金森病的康复:病例报告。

Rehabilitation in primary lateral sclerosis mimicking parkinsonism: A case report.

机构信息

Department of Medical and Surgical Sciences, Magna Græcia University of Catanzaro, Catanzaro, Calabria, Italy.

出版信息

NeuroRehabilitation. 2020;47(4):381-386. doi: 10.3233/NRE-201527.

DOI:10.3233/NRE-201527
PMID:33164952
Abstract

BACKGROUND

Primary lateral sclerosis (PLS) is an upper motor neurons disease that on rare occasions may determine bradykinesia and motor fatigue. To date, no rehabilitative treatment has been described as useful for these patients.

CASE PRESENTATION

A 68-year-old male developed dysarthria, spastic laugh, impairments of handwriting and fine motor, gait and dysphagia disorders for both solids and liquids over the period from 2015 to December 2018, with normal DaT scans and no clinical benefits from therapy with levodopa, pramipexole and baclofen. The patient underwent exercises for gait training and balance control with sensory treadmill and stabilometric platform and kinesiotherapy to improve fine motor skills of both hands and postural changes, five days a week for two weeks. Based on our data, the patient showed an improvement in balance and gait parameters in T2 compared to T1.

CONCLUSION

Thanks to the synergistic action of a combined treatment of physical and instrumental therapy, despite the rare pathology and complex disability, the patient had important benefits in terms of performance and independence in daily activity.

摘要

背景

原发性侧索硬化症(PLS)是一种上运动神经元疾病,在极少数情况下可能导致运动迟缓及运动性疲劳。迄今为止,尚无康复治疗被描述为对这些患者有效。

病例介绍

一名 68 岁男性于 2015 年至 2018 年 12 月期间出现构音障碍、痉挛性笑、书写和精细运动受损、步态障碍和吞咽固体及液体困难,DaT 扫描正常,且左旋多巴、普拉克索和巴氯芬治疗无临床获益。患者接受了步态训练和平衡控制的运动训练,使用感觉跑步机和平衡台以及运动疗法来改善双手的精细运动技能和姿势变化,每周五天,持续两周。根据我们的数据,与 T1 相比,患者在 T2 时的平衡和步态参数有所改善。

结论

尽管该疾病罕见且残疾复杂,但由于物理和仪器治疗的协同作用,患者在日常活动的表现和独立性方面获得了重要的益处。

相似文献

1
Rehabilitation in primary lateral sclerosis mimicking parkinsonism: A case report.原发性侧索硬化症表现类似帕金森病的康复:病例报告。
NeuroRehabilitation. 2020;47(4):381-386. doi: 10.3233/NRE-201527.
2
Vestibular rehabilitation has positive effects on balance, fatigue and activities of daily living in highly disabled multiple sclerosis people: A preliminary randomized controlled trial.前庭康复对重度残疾的多发性硬化症患者的平衡、疲劳及日常生活活动有积极影响:一项初步随机对照试验。
Restor Neurol Neurosci. 2018;36(6):709-718. doi: 10.3233/RNN-180850.
3
Erratum.勘误
Mult Scler. 2016 Oct;22(12):NP9-NP11. doi: 10.1177/1352458515585718. Epub 2015 Jun 3.
4
Primary lateral sclerosis plus parkinsonism: a case report.原发性侧索硬化合并帕金森病:病例报告。
BMC Neurol. 2023 Aug 29;23(1):312. doi: 10.1186/s12883-023-03360-x.
5
The effects of loading and unloading treadmill walking on balance, gait, fall risk, and daily function in Parkinsonism.加载和卸载跑步机步行对帕金森病患者平衡、步态、跌倒风险及日常功能的影响。
NeuroRehabilitation. 2005;20(4):307-22.
6
Comparison of Cawthorne-Cooksey exercises and sinusoidal support surface translations to improve balance in patients with unilateral vestibular deficit.比较Cawthorne-Cooksey训练法与正弦支撑面平移训练对改善单侧前庭功能减退患者平衡能力的效果。
Arch Phys Med Rehabil. 2003 Aug;84(8):1173-84. doi: 10.1016/s0003-9993(03)00130-8.
7
The effect of the rehabilitation program on balance, gait, physical performance and trunk rotation in Parkinson's disease.康复计划对帕金森病患者平衡、步态、身体功能及躯干旋转的影响。
Aging Clin Exp Res. 2016 Dec;28(6):1169-1177. doi: 10.1007/s40520-015-0506-1. Epub 2015 Dec 10.
8
Parkinsonism and motor neuron diseases: twenty-seven patients with diverse overlap syndromes.帕金森病和运动神经元病:27 例具有多种重叠综合征的患者。
Mov Disord. 2010 Sep 15;25(12):1868-75. doi: 10.1002/mds.23200.
9
The effectiveness of Robot-Assisted Gait Training versus conventional therapy on mobility in severely disabled progressIve MultiplE sclerosis patients (RAGTIME): study protocol for a randomized controlled trial.机器人辅助步态训练与传统疗法对重度残疾进展性多发性硬化症患者活动能力的疗效比较(RAGTIME):一项随机对照试验的研究方案
Trials. 2017 Feb 27;18(1):88. doi: 10.1186/s13063-017-1838-2.
10
Does extending the dual-task functional exercises workout improve postural balance in individuals with ID?延长双重任务功能锻炼训练是否能改善智障人士的姿势平衡?
Res Dev Disabil. 2015 Mar;38:84-91. doi: 10.1016/j.ridd.2014.12.008. Epub 2014 Dec 29.

引用本文的文献

1
Primary lateral sclerosis plus parkinsonism: a case report.原发性侧索硬化合并帕金森病:病例报告。
BMC Neurol. 2023 Aug 29;23(1):312. doi: 10.1186/s12883-023-03360-x.