Department of Physiotherapy, Faculty of Health Sciences, Universitas Muhammadiyah, Surakarta, Indonesia.
Department of Neurology, Faculty of Medicine, Universitas Gadjah Mada Yogyakarta, Indonesia.
NeuroRehabilitation. 2020;47(4):463-470. doi: 10.3233/NRE-203210.
Brain injuries such as strokes cause damage and death of the neuron cells. Physiotherapy interventions help to improve patient's performance and ability. However, this is only theorized but the impact of the physiotherapy intervention on brain plasticity is not known.
The present study aimed to investigate the effect of physiotherapy interventions on brain neuroplasticity by evaluating the brain plasticity regeneration, balance and functional ability.
A randomized controlled trial was conducted with 64 stroke patients from three hospitals in the Surakarta region, Indonesia. Control groups (n = 32) received conventional physiotherapy and intervention groups (n = 32) received neurorestoration protocol, which both lasted for seven days. Efficacy of the interventions were measured on brain-derived neurotropic factor serum analysis, Berg Balance Scale and Barthel Index, respectively.
Both groups showed improvements in all parameters but only balance and functional performance had a statistically significant outcome.
Neurorestoration protocol that combined several established physiotherapy interventions was effective in improving balance and functional ability of stroke patients in only a seven days period.
脑损伤，如中风，会导致神经元细胞的损伤和死亡。物理治疗干预有助于提高患者的表现和能力。然而，这只是理论上的，物理治疗干预对大脑可塑性的影响尚不清楚。
本研究旨在通过评估大脑可塑性的再生、平衡和功能能力，来研究物理治疗干预对大脑神经可塑性的影响。
对印度尼西亚苏拉卡尔塔地区的三家医院的 64 名中风患者进行了一项随机对照试验。对照组（n=32）接受常规物理治疗，干预组（n=32）接受神经修复方案治疗，两组均持续七天。分别通过血清脑源性神经营养因子分析、伯格平衡量表和巴氏指数来评估干预措施的疗效。
两组患者在所有参数上都有改善，但只有平衡和功能表现有统计学上的显著效果。
神经修复方案结合了几种已确立的物理治疗干预措施，仅在七天的时间内就有效地改善了中风患者的平衡和功能能力。
