From the Department of Plastic Surgery, Medical College of Wisconsin.
Plast Reconstr Surg. 2021 Feb 1;147(2):319-327. doi: 10.1097/PRS.0000000000007518.
Anatomical studies have identified separate superficial and deep facial fat compartments, leading some to theorize that volume loss from the deep midface causes overlying superficial fat pseudoptosis. Unfortunately, a paucity of evidence exists regarding whether facial fat volume is truly lost with age and, if so, whether it is lost equally or differentially from the superficial and deep compartments. The aim of this study was to quantify volume changes occurring with age within the superficial, deep, and buccal fat compartments of the midface.
A retrospective longitudinal study was performed evaluating individuals aged 30 to 65 years who underwent facial computed tomography followed by facial computed tomography greater than or equal to 10 years later. Superficial midface, deep midface, and buccal fat volumes were quantified using Horos radiology software.
Nineteen subjects met inclusion criteria. Mean total fat volume decreased significantly from 46.47 cc to 40.81 cc (p < 0.01). The mean superficial and deep fat volumes both decreased significantly from 26.10 cc to 23.15 cc (p < 0.01) and from 11.01 cc to 8.98 cc (p < 0.01), respectively. No significant difference was observed in buccal fat volume over time (9.36 cc to 8.68 cc; p = 0.04). Patients lost an average of 11.3 percent of their initial superficial fat volume and 18.4 percent of their initial deep fat volume.
Significant volume loss was observed from both superficial and deep facial fat compartments over a mean 11.3 years. Patients lost a greater percentage of deep facial fat volume, providing support for the theory of pseudoptosis caused by deep midface fat loss.
解剖学研究已经确定了面部浅层和深层脂肪隔室是分开的，这使得一些人推测深层中面部的体积减少会导致上方的浅层脂肪假性下垂。不幸的是，关于面部脂肪体积是否真的随着年龄的增长而减少，以及如果是这样，它是否从浅层和深层隔室均匀或差异地减少，证据很少。本研究旨在定量测量中面部浅层、深层和颊脂垫脂肪隔室随年龄增长而发生的体积变化。
回顾性纵向研究评估了年龄在 30 至 65 岁之间的个体，他们接受了面部 CT 检查，然后至少 10 年后再次接受了面部 CT 检查。使用 Horos 放射学软件定量测量浅层中面部、深层中面部和颊脂垫的体积。
19 名受试者符合纳入标准。总脂肪体积从 46.47cc 显著减少到 40.81cc（p<0.01）。浅层和深层脂肪体积均从 26.10cc 显著减少到 23.15cc（p<0.01）和从 11.01cc 显著减少到 8.98cc（p<0.01）。颊脂垫体积在时间上没有显著差异（9.36cc 至 8.68cc；p=0.04）。患者平均失去了其初始浅层脂肪体积的 11.3%和初始深层脂肪体积的 18.4%。
在平均 11.3 年的时间里，观察到浅层和深层面部脂肪隔室都有明显的体积减少。患者失去了更多的深层面部脂肪体积，这支持了由于深层中面部脂肪减少导致假性下垂的理论。
