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本文引用的文献

1
Electronic Cigarette or Vaping-associated Lung Injury (EVALI): The Tip of the Iceberg.电子烟或雾化相关肺损伤(EVALI):冰山一角
Radiol Cardiothorac Imaging. 2019 Oct 31;1(4):e190212. doi: 10.1148/ryct.2019190212. eCollection 2019 Oct.
2
Vaping-induced diffuse alveolar hemorrhage.电子烟诱发的弥漫性肺泡出血。
Respir Med Case Rep. 2020 Jan 7;29:100996. doi: 10.1016/j.rmcr.2020.100996. eCollection 2020.
3
The EVALI and Youth Vaping Epidemics - Implications for Public Health.电子烟或雾化产品使用相关肺损伤(EVALI)与青少年电子烟流行——对公共卫生的影响
N Engl J Med. 2020 Feb 20;382(8):689-691. doi: 10.1056/NEJMp1916171. Epub 2020 Jan 17.
4
E-cigarette, or vaping, product use associated lung injury (EVALI): case series and diagnostic approach.电子烟或蒸气烟产品使用相关肺损伤(EVALI):病例系列和诊断方法。
Lancet Respir Med. 2019 Dec;7(12):1017-1026. doi: 10.1016/S2213-2600(19)30415-1. Epub 2019 Nov 8.
5
Update: Interim Guidance for Health Care Providers Evaluating and Caring for Patients with Suspected E-cigarette, or Vaping, Product Use Associated Lung Injury - United States, October 2019.更新:美国 2019 年 10 月,医疗保健提供者评估和护理疑似电子烟或蒸气产品使用相关肺损伤患者的临时指南。
MMWR Morb Mortal Wkly Rep. 2019 Oct 18;68(41):919-927. doi: 10.15585/mmwr.mm6841e3.
6
Recurrent spontaneous pneumothoraces and vaping in an 18-year-old man: a case report and review of the literature.一名18岁男性复发性自发性气胸与电子烟使用:病例报告及文献综述
J Med Case Rep. 2019 Sep 9;13(1):283. doi: 10.1186/s13256-019-2215-4.
7
E-cigarette vapour enhances pneumococcal adherence to airway epithelial cells.电子烟蒸汽增强肺炎链球菌对气道上皮细胞的黏附。
Eur Respir J. 2018 Feb 7;51(2). doi: 10.1183/13993003.01592-2017. Print 2018 Feb.
8
Organizing pneumonia related to electronic cigarette use: A case report and review of literature.与电子烟使用相关的机化性肺炎:一例病例报告及文献综述
Clin Respir J. 2018 Mar;12(3):1295-1299. doi: 10.1111/crj.12775. Epub 2018 Feb 22.
9
E-Cigarette Use Causes a Unique Innate Immune Response in the Lung, Involving Increased Neutrophilic Activation and Altered Mucin Secretion.电子烟使用在肺部引起独特的先天免疫反应,涉及中性粒细胞激活增加和粘蛋白分泌改变。
Am J Respir Crit Care Med. 2018 Feb 15;197(4):492-501. doi: 10.1164/rccm.201708-1590OC.

电子烟使用导致的肺部损伤:一团有害且致命的蒸汽。

Lung injury from e-cigarette use: a foul and pestilent congregation of vapours.

作者信息

Chapman Robert, Tweed Conor D, Moonsie Ian

机构信息

Respiratory Medicine Department, North Middlesex University Hospital NHS Trust, London, UK

Respiratory Medicine Department, North Middlesex University Hospital NHS Trust, London, UK.

出版信息

BMJ Case Rep. 2020 Nov 9;13(11):e237338. doi: 10.1136/bcr-2020-237338.

DOI:10.1136/bcr-2020-237338
PMID:33168537
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7654138/
Abstract

A 62-year-old man presented with worsening dyspnoea, haemoptysis and reduced exercise tolerance. He was found to be hypoxaemic with bilateral basal opacification on chest imaging, but inflammatory markers, respiratory virus PCR and sputum culture demonstrated no signs of infection. The patient reported having initially mild, yet progressive, symptoms since he started vaping 14 months previously. He was treated with oxygen therapy, supportive care and cessation of vaping. Chest imaging at discharge showed marked improvement of previous bilateral opacification and the patient returned to baseline exercise tolerance, with no oxygen requirement. Vaping is becoming more common in the UK and this case demonstrates the importance of considering electronic vaping-associated lung injury in cases of non-infective lung injury.

摘要

一名62岁男性出现呼吸困难、咯血加重及运动耐量下降。胸部影像学检查发现他存在低氧血症且双侧肺底部有混浊影,但炎症指标、呼吸道病毒聚合酶链反应(PCR)及痰培养均未显示感染迹象。患者自述自14个月前开始吸电子烟以来,最初症状轻微,但呈进行性加重。他接受了氧疗、支持治疗并停止吸电子烟。出院时的胸部影像学检查显示先前双侧混浊影明显改善,患者恢复至基线运动耐量,无需吸氧。吸电子烟在英国正变得越来越普遍,该病例表明在非感染性肺损伤病例中考虑与电子烟相关的肺损伤的重要性。