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面对伦理挑战:消费者参与 COVID-19 大流行研究。

Facing the Ethical Challenges: Consumer Involvement in COVID-19 Pandemic Research.

机构信息

Australian Clinical Trials Alliance, Suite 1, Level 2, 24 Albert Road, Melbourne, VIC, 3205, Australia.

Telethon Kids Institute, Consumer Engagement, Perth, Australia.

出版信息

J Bioeth Inq. 2020 Dec;17(4):743-748. doi: 10.1007/s11673-020-10060-5. Epub 2020 Nov 9.

Abstract

Consumer involvement in clinical research is an essential component of a comprehensive response during emergent health challenges. During the COVID-19 pandemic, the moderation of research policies and regulation to facilitate research may raise ethical issues. Meaningful, diverse consumer involvement can help to identify practical approaches to prioritize, design, and conduct rapidly developed clinical research amid current events. Consumer involvement might also elucidate the acceptability of flexible ethics review approaches that aim to protect participants whilst being sensitive to the challenging context in which research is taking place. This article describes the main ethical challenges arising from pandemic research and how involving consumers and the community could enable resolution of such issues.

摘要

消费者参与临床研究是应对紧急健康挑战的全面应对措施的重要组成部分。在 COVID-19 大流行期间,为促进研究而调整研究政策和法规可能会引发伦理问题。有意义的、多样化的消费者参与有助于确定在当前情况下优先考虑、设计和开展快速开发的临床研究的实用方法。消费者的参与还可以阐明灵活的伦理审查方法的可接受性,这些方法旨在保护参与者,同时对研究进行的具有挑战性的背景保持敏感。本文描述了大流行研究中出现的主要伦理挑战,以及如何让消费者和社区参与解决这些问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7cfa/7651817/deb40815d83a/11673_2020_10060_Fig1_HTML.jpg

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