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对新冠肺炎患者成像中的心脏检查结果进行量化和报告。

Quantifying and reporting cardiac findings in imaging of COVID-19 patients.

作者信息

Mishra Ajay Kumar, Lal Amos, Sahu Kamal Kant, Kranis Mark, Sargent Jennifer

机构信息

Department of Medicine, Saint Vincent Hospital, Worcester, MA.

Department of Medicine, Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN.

出版信息

Monaldi Arch Chest Dis. 2020 Nov 9;90(4). doi: 10.4081/monaldi.2020.1394.

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection continues to be a public health emergency and a pandemic of international concern. As of April 31st,  the reported cases of COVID-19 are three million in 186 countries. Reported case fatality has crossed 200 thousand among which more than fifty thousand has been in the USA. Most patients present with symptoms of fever, cough, and shortness of breath following exposure to other COVID-19 patients. Respiratory manifestations predominate in patients with mild, moderate, severe illness. Imaging of patients with COVID-19 consistently reports various pulmonary parenchymal involvement. In this article we wanted to reinforce and review the various reported imaging patterns of cardiac and mediastinal involvement in COVID-19 patients. Among patients with COVID 19 who underwent various imaging of chest various cardiac findings including pericardial effusion, myocarditis, cardiomegaly has been reported. Most of these findings have been consistently reported in patients with significant acute myocardial injury, and fulminant myocarditis. Acute biventricular dysfunction has also been reported with subsequent improvement of the same following clinical improvement. Details of cardiac MRI is rather limited. In a patient with clinical presentation of acute myocarditis, biventricular myocardial interstitial edema, diffuse biventricular hypokinesia, increased ventricular wall thickness, and severe LV dysfunction has been reported. Among patients with significant clinical improvement in LV structure and function has also been documented. With increasing number of clinical cases, future imaging studies will be instrumental in identifying the various cardiac manifestations, and their relation to clinical outcome.

摘要

严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染仍是突发公共卫生事件,是国际关注的大流行病。截至4月31日,186个国家报告的新型冠状病毒肺炎病例达300万例。报告的死亡病例已超过20万例,其中美国超过5万例。大多数患者在接触其他新型冠状病毒肺炎患者后出现发热、咳嗽和呼吸急促症状。轻度、中度、重度患者均以呼吸道表现为主。新型冠状病毒肺炎患者的影像学检查一直报告有各种肺实质受累情况。在本文中,我们想强化并回顾新型冠状病毒肺炎患者心脏和纵隔受累的各种已报道的影像学表现。在接受胸部各种影像学检查的新型冠状病毒肺炎患者中,已报告了包括心包积液、心肌炎、心脏扩大等各种心脏检查结果。这些发现大多在有严重急性心肌损伤和暴发性心肌炎的患者中得到一致报告。也有急性双心室功能障碍的报告,随后随着临床症状改善而好转。心脏磁共振成像的细节相当有限。在一名临床表现为急性心肌炎的患者中,已报告有双心室心肌间质水肿、双心室弥漫性运动减弱、心室壁增厚和严重的左心室功能障碍。在左心室结构和功能有显著临床改善的患者中也有记录。随着临床病例数量的增加,未来的影像学研究将有助于识别各种心脏表现及其与临床结局的关系。

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