Higuchi I, Ishiura S, Nonaka I, Sugita H
National Center for Nervous, Mental and Muscular Disorders, Tokyo, Japan.
Muscle Nerve. 1987 Nov-Dec;10(9):790-800. doi: 10.1002/mus.880100904.
High AMP deaminase reactivity was detected in the rimmed vacuoles in skeletal muscles in adult onset acid maltase deficiency and distal myopathy with rimmed vacuole formation histochemically as well as immunohistochemically. Acid phosphatase activity was positive but myosin ATPase activity was negative in the vacuoles. AMP deaminase found in rimmed vacuoles does not seem to be associated with myosin but is possibly bound to lysosomes or other related organelles in accordance with the proliferation of autophagic vacuoles.
在成人起病的酸性麦芽糖酶缺乏症和伴有镶边空泡形成的远端肌病的骨骼肌镶边空泡中，通过组织化学和免疫组织化学检测到高AMP脱氨酶反应性。空泡中的酸性磷酸酶活性呈阳性，但肌球蛋白ATP酶活性呈阴性。在镶边空泡中发现的AMP脱氨酶似乎与肌球蛋白无关，但可能根据自噬空泡的增殖与溶酶体或其他相关细胞器结合。
