• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

哮喘吸入治疗的多学科共识。

Multidisciplinary consensus on inhaled therapy in asthma.

机构信息

Allergy Unit, Pneumology Department, Hospital Clínic, IDIBAPS, CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Spain.

Menasalbas Primary Health-Care Center, Toledo, Spain.

出版信息

Expert Rev Respir Med. 2021 Mar;15(3):425-434. doi: 10.1080/17476348.2021.1841639. Epub 2020 Nov 10.

DOI:10.1080/17476348.2021.1841639
PMID:33170733
Abstract

BACKGROUND

Asthma is managed by health professionals from different specialties. We aim to reach a consensus on the optimal use of inhaled therapy and the initial steps of asthma treatment, taking into account the opinions of the involved specialists.

METHODS

A modified Delphi approach was used. A scientific committee provided 52 controversial statements, which were submitted to primary care physicians, allergists, and pulmonologists. Discrepancies among specialties were evaluated.

RESULTS

A total of 209 specialists completed the questionnaire (20.2 ± 9.3 years of asthma management experience). A consensus was reached on 37 statements (71.1%), discrepancies among specialties were found in 14. The most recommended maintenance treatment for mild persistent asthma in adults/adolescents was low-dose-inhaled corticosteroids daily. MART (Maintenance and Reliever Therapy) was recommended as salvage treatment for moderate persistent asthma. Panelists agreed on the most frequent critical errors with pressurized Metered-Dose Inhalers or Dry-Powder Inhalers, and considered that Breath-Actuated Inhalers are a suitable option for all patients with the ability to inhale voluntarily.

CONCLUSIONS

The experts endorse the main guidelines recommendations; however, do not fully agree on recent GINA recommendations about the treatment of the initial steps of the disease. The experts value positively the differential characteristics of BAI over other devices.

摘要

背景

哮喘由不同专业领域的医疗保健专业人员管理。我们旨在就吸入疗法的最佳使用以及哮喘治疗的初始步骤达成共识,同时考虑到相关专家的意见。

方法

采用改良 Delphi 法。一个科学委员会提供了 52 个有争议的陈述,这些陈述被提交给初级保健医生、过敏症专家和肺病专家。评估了专业之间的差异。

结果

共有 209 名专家完成了问卷(哮喘管理经验 20.2±9.3 年)。就 37 项声明达成共识(71.1%),专业之间存在差异的有 14 项。成人/青少年轻度持续性哮喘的最推荐维持治疗是低剂量吸入皮质激素每日治疗。MART(维持和缓解治疗)被推荐为中度持续性哮喘的补救治疗。专家组同意关于加压计量吸入器或干粉吸入器最常见的关键错误,并认为呼吸驱动式吸入器是所有具有自愿吸入能力的患者的合适选择。

结论

专家们认可主要指南推荐;然而,他们不完全同意 GINA 最近关于疾病初始阶段治疗的建议。专家们对 BAI 的差异特征给予了积极的评价,优于其他设备。

相似文献

1
Multidisciplinary consensus on inhaled therapy in asthma.哮喘吸入治疗的多学科共识。
Expert Rev Respir Med. 2021 Mar;15(3):425-434. doi: 10.1080/17476348.2021.1841639. Epub 2020 Nov 10.
2
Asthma control in patients receiving inhaled corticosteroid and long-acting beta2-agonist fixed combinations. A real-life study comparing dry powder inhalers and a pressurized metered dose inhaler extrafine formulation.吸入性皮质类固醇和长效β2-激动剂固定组合治疗患者的哮喘控制情况。一项真实世界研究比较干粉吸入器和压力定量气雾剂超细配方。
BMC Pulm Med. 2011 Jul 15;11:40. doi: 10.1186/1471-2466-11-40.
3
Comparison of the effectiveness of inhaler devices in asthma and chronic obstructive airways disease: a systematic review of the literature.吸入装置在哮喘和慢性阻塞性气道疾病中的有效性比较:文献系统评价
Health Technol Assess. 2001;5(26):1-149. doi: 10.3310/hta5260.
4
Breath-actuated INhalation TheRapy: survey of phySicians' PErCepTion (INTROSPECT) in Nepal.呼吸驱动吸入治疗:尼泊尔医生认知调查(内省)。
J Asthma. 2023 Aug;60(8):1545-1552. doi: 10.1080/02770903.2022.2158858. Epub 2023 Feb 2.
5
Real-life effectiveness of inhaler device switch from dry powder inhalers to pressurized metred-dose inhalers in patients with asthma treated with ICS/LABA.在接受 ICS/LABA 治疗的哮喘患者中,从干粉吸入器切换至压力定量气雾剂吸入器的真实世界疗效。
Respirology. 2019 Oct;24(10):972-979. doi: 10.1111/resp.13559. Epub 2019 Apr 30.
6
An innovative corticosteroid/long-acting β-agonist breath-triggered inhaler: facilitating lung delivery of fluticasone propionate/formoterol fumarate for the treatment of asthma.一种创新的皮质类固醇/长效β-激动剂呼气触发式吸入器:促进丙酸氟替卡松/富马酸福莫特罗在肺部的递送,用于哮喘治疗。
Expert Opin Drug Deliv. 2019 Dec;16(12):1367-1380. doi: 10.1080/17425247.2019.1689957. Epub 2019 Nov 28.
7
What drives inhaler prescription for asthma patients? Results from a real-life retrospective analysis.是什么驱动哮喘患者使用吸入器处方?真实世界回顾性分析的结果。
Respir Med. 2020 May;166:105937. doi: 10.1016/j.rmed.2020.105937. Epub 2020 Mar 20.
8
Systematic review and economic analysis of the comparative effectiveness of different inhaled corticosteroids and their usage with long-acting beta2 agonists for the treatment of chronic asthma in adults and children aged 12 years and over.不同吸入性糖皮质激素及其与长效β2受体激动剂联合使用治疗12岁及以上成人和儿童慢性哮喘比较效果的系统评价与经济学分析
Health Technol Assess. 2008 May;12(19):iii-iv, 1-360. doi: 10.3310/hta12190.
9
Twenty-five statements on early initiation of fixed combination ICS/LABA treatment for asthma and COPD in primary and secondary care: consensus research by a modified Delphi process.关于在初级和二级医疗保健中对哮喘和慢性阻塞性肺疾病(COPD)早期启动吸入性糖皮质激素/长效β2受体激动剂(ICS/LABA)联合治疗的25条声明:通过改良德尔菲法进行的共识研究
Pneumologie. 2012 Sep;66(9):549-57. doi: 10.1055/s-0032-1310076. Epub 2012 Aug 16.
10
Asthma medication delivery: mists and myths.哮喘药物输送:迷雾与误解。
Paediatr Respir Rev. 2013 Jun;14(2):112-8; quiz 118, 137-8. doi: 10.1016/j.prrv.2013.02.013. Epub 2013 Mar 21.