外骨骼辅助行走对脊髓损伤患者软组织身体成分的影响。
Effect of Exoskeletal-Assisted Walking on Soft Tissue Body Composition in Persons With Spinal Cord Injury.
机构信息
National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters VA Medical Center, Bronx, NY; Department of Rehabilitation and Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY.
National Center for the Medical Consequences of Spinal Cord Injury, James J. Peters VA Medical Center, Bronx, NY.
出版信息
Arch Phys Med Rehabil. 2021 Feb;102(2):196-202. doi: 10.1016/j.apmr.2020.07.018. Epub 2020 Nov 7.
OBJECTIVE
To determine the effect of overground walking using a powered exoskeleton on soft tissue body composition in persons with spinal cord injury (SCI).
DESIGN
A prospective, single group observational pilot study.
SETTING
Medical center.
PARTICIPANTS
Persons (N=8) with chronic (>6mo) SCI between 18 and 65 years old who weighed less than 100 kg.
INTERVENTIONS
Overground ambulation training using a powered exoskeleton (ReWalk) for 40 sessions, with each session lasting up to 2 hours, with participants training 3 times per week.
MAIN OUTCOME MEASURE(S): Dual-energy x-ray absorptiometry (DXA) was used to measure lean mass (LM) and fat mass (FM) from the whole body, arms, legs and trunk. DXA was also used to assess visceral adipose tissue (VAT). Walking performance was measured by 6-minute walk test.
RESULTS
Participants significantly lost total body FM (-1.8±1.2kg, P=.004) with the loss of adiposity distributed over several regional sites. Six of the 8 participants lost VAT, with the average loss in VAT trending toward significance (-0.141kg, P=.06). LM for the group was not significantly changed.
CONCLUSIONS
Sustained and weekly use of powered exoskeletons in persons with SCI has the potential to reduce FM with inferred improvements in health.
目的
确定使用动力外骨骼在地面行走对脊髓损伤（SCI）患者软组织身体成分的影响。
设计
前瞻性、单组观察性初步研究。
地点
医疗中心。
参与者
8 名年龄在 18 至 65 岁之间、慢性（>6 个月）SCI、体重低于 100 公斤的 SCI 患者。
干预措施
使用动力外骨骼（ReWalk）进行 40 次地面步行训练，每次持续长达 2 小时，参与者每周训练 3 次。
主要观察指标
双能 X 线吸收法（DXA）用于测量全身、手臂、腿部和躯干的瘦体重（LM）和脂肪量（FM）。DXA 还用于评估内脏脂肪组织（VAT）。行走能力通过 6 分钟步行测试进行测量。
结果
参与者的总体体脂 FM 显著减少（-1.8±1.2kg，P=.004），脂肪减少分布在多个区域。8 名参与者中有 6 名的 VAT 减少，VAT 的平均减少有显著趋势（-0.141kg，P=.06）。但组内的 LM 没有显著变化。
结论
脊髓损伤患者持续且每周使用动力外骨骼可能会减少 FM，从而推断出健康状况得到改善。
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