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子痫前期:病理生理学与管理。

Preeclampsia: Pathophysiology and management.

机构信息

Department of Cellular and Molecular Physiology, Penn State College of Medicine, Hershey, United States.

Department of Biochemistry, CSIR-CFTRI, Mysuru, 570020, India.

出版信息

J Gynecol Obstet Hum Reprod. 2021 Feb;50(2):101975. doi: 10.1016/j.jogoh.2020.101975. Epub 2020 Nov 7.

Abstract

Preeclampsia is a pregnancy-related multisystem disorder, frequently encountered pregnancy-related medical complications next to gestational diabetes mellitus. It is the onset of hypertension during pregnancy. The preeclampsia can be of two types, placental or maternal preeclampsia. Among these two types former, i.e., placental preeclampsia is more severe than the latter. According to the recent survey by National Health Portal of India, the incidence of preeclampsia is about 8-10 % among pregnant women. Though our understanding of preeclampsia has improved in recent years, the development and interpretation of the clinical tests remain difficult for preeclampsia. Hence, we have made an attempt to understand the pathophysiology, associated conditions/consequences, treatment and management/prevention of the condition in this review.

摘要

子痫前期是一种与妊娠相关的多系统疾病,是仅次于妊娠期糖尿病的常见妊娠相关医疗并发症。它是妊娠期间高血压的发作。子痫前期可分为胎盘型或母体型子痫前期。这两种类型中,前者即胎盘型子痫前期比后者更为严重。根据印度国家健康门户网站的最新调查,子痫前期在孕妇中的发病率约为 8-10%。尽管我们近年来对子痫前期的认识有所提高,但临床检测的发展和解释仍然很困难。因此,我们试图在本综述中了解该病症的病理生理学、相关情况/后果、治疗和管理/预防。

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