Shirinzad Mehdi, Dalir Mohammad Moradi, Tiznobaik Azita, Kazemi Farideh, Momenimovahed Zohreh
Department of Restorative Dentistry, School of Dentistry, Hamadan University of Medical Sciences, Hamadan, Iran.
Mother and Child Care Research Center, Institute of Health Sciences and Technologies, Hamadan University of Medical Sciences, Hamadan, Iran.
Clin Exp Dent Res. 2025 Aug;11(4):e70177. doi: 10.1002/cre2.70177.
This study investigates the association between Decayed, Missing, and Filled Teeth (DMFT) Index, dental plaque (assessed via Plaque Index [PI]), and pre-eclampsia in pregnant women.
A case-control study was conducted with 70 pregnant women diagnosed with pre-eclampsia (cases) and 70 without (controls), matched for demographic and obstetric variables. Data were collected using a checklist capturing demographic details, obstetric history, and oral health parameters (DMFT and PI). Statistical analyses included chi-square tests, independent t-tests, and multiple logistic regression.
The case group exhibited a significantly higher mean DMFT index (11.70 ± 2.88 vs. 9.21 ± 2.24, p < 0.001) and PI (33.26 ± 9.21 vs. 28.30 ± 7.26, p < 0.001) compared to controls. Each one-unit increase in the DMFT index and PI was associated with 19% and 5% increased odds of pre-eclampsia, respectively (p < 0.001).
Dental caries and plaque are significantly associated with pre-eclampsia in pregnant women. Integrating oral health assessments into antenatal care is recommended to mitigate these risks and improve maternal and fetal outcomes.
本研究调查孕妇的龋失补牙指数（DMFT指数）、牙菌斑（通过菌斑指数[PI]评估）与子痫前期之间的关联。
进行了一项病例对照研究，选取70例被诊断为子痫前期的孕妇（病例组）和70例未患子痫前期的孕妇（对照组），根据人口统计学和产科变量进行匹配。使用一份清单收集数据，该清单涵盖人口统计学细节、产科病史和口腔健康参数（DMFT和PI）。统计分析包括卡方检验、独立t检验和多元逻辑回归。
与对照组相比，病例组的平均DMFT指数（11.70±2.88对9.21±2.24，p<0.001）和PI（33.26±9.21对28.30±7.26，p<0.001）显著更高。DMFT指数和PI每增加一个单位，子痫前期的发生几率分别增加19%和5%（p<0.001）。
龋齿和牙菌斑与孕妇子痫前期显著相关。建议将口腔健康评估纳入产前护理，以降低这些风险并改善母婴结局。
