Touret M, Kitahama K, Geffard M, Jouvet M
Département de Médecine Expérimentale, Faculté de Médecine, Université Claude Bernard, Lyon, France.
Neurosci Lett. 1987 Oct 5;80(3):263-7. doi: 10.1016/0304-3940(87)90465-4.
We demonstrated the presence of 5-hydroxytryptophan (5-HTP), the immediate precursor of serotonin (5-HT), in the rat brain tissue using a glutaraldehyde-coupled immunohistochemical technique. The immunoreactivity of 5-HTP was intensified in the colchicine-pretreated rat. The distribution of labelled cells was the same as for 5-HT-immunoreactive cells, but they were fewer in number.
