Safar M E, Bouthier J A, Laurent S M, Simon A C
The Diagnostic Centre, Broussais Hospital, Paris, France.
Postgrad Med J. 1986;62 Suppl 1:31-3.
The haemodynamic pattern of the common carotid artery was studied before and after administration of captopril isosorbide dinitrate and nitrendipine, in men with sustained essential hypertension. Pulsed Doppler methods were used. Captopril produced both a fall in vascular resistance and an increase in the arterial diameter of the common carotid artery. Thus, in the common carotid artery circulation of patients with essential hypertension only captopril dilated both small and large arteries.
在患有持续性原发性高血压的男性中,研究了服用卡托普利、硝酸异山梨酯和尼群地平前后颈总动脉的血流动力学模式。采用脉冲多普勒方法。卡托普利可降低血管阻力并增加颈总动脉的动脉直径。因此,在原发性高血压患者的颈总动脉循环中,只有卡托普利能使小动脉和大动脉都扩张。