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识别择期结直肠手术老年患者术后肺部并发症的危险因素。

Identification of the Risk Factors of Postoperative Pulmonary Complications in Elderly Patients Undergoing Elective Colorectal Surgery.

机构信息

Department of Anesthesiology, The Affiliated Sheng Jing Hospital of China Medical University, Shenyang, China.

Department of Anesthesiology, Central South Hospital of Wuhan University, Wuhan, China.

出版信息

Am Surg. 2021 May;87(5):777-783. doi: 10.1177/0003134820950304. Epub 2020 Nov 11.

Abstract

OBJECTIVE

This study was to identify the perioperative related risk factors of postoperative pulmonary complications (PPCs) in elderly patients undergoing elective colorectal surgery, which will provide new insight for better prevention and intervention of PPCs in elderly patients.

METHODS

A retrospective study involving 445 patients (age ≥65), who registered in Shengjing Hospital affiliated to China Medical University for elective colorectal surgery from October 2014 to March 2017, was conducted. Clinical data, including demographic information, medical history, preoperative examination, and surgery-related factors, were analyzed and compared between the patient group with PPCs and the group without PPCs. t-test or χ test was performed for statistical analysis between the 2 groups. Binary logistic regression analysis was further employed to identify the potential independent risk factors of PPCs.

RESULTS

Among the 445 patients enrolled in the study, 49 (11%) had PPCs, while 396 (89%) did not. The main risk factors of PPC occurrence in the elderly patients undergoing elective colorectal surgery included older age (age ≥75 years), ASA >II, hypertension, myocardial ischemia, basic pulmonary diseases, laparotomy, blood transfusion, preoperative hemoglobin <100 g/L, and albumin <35 g/L. Laparotomy (compared with laparoscope) and ASA >II were independent risk factors for the increased incidence of PPCs.

CONCLUSION

More attention should be paid to patients with older age and ASA >II in elective colorectal surgery. Choice of laparoscopic operation, proper treatment of hypertension, myocardial ischemia, basic pulmonary diseases, and correction of anemia and nutritional status can effectively reduce the incidence of PPCs. An adequate and comprehensive evaluation of the potential risk factors related to PPCs is required before surgery.

摘要

目的

本研究旨在确定择期结直肠手术老年患者术后肺部并发症(PPC)的围手术期相关危险因素,为老年患者 PPC 的更好预防和干预提供新的见解。

方法

回顾性分析 2014 年 10 月至 2017 年 3 月在中国医科大学附属盛京医院行择期结直肠手术的 445 例(年龄≥65 岁)患者的临床资料,包括人口统计学信息、病史、术前检查和手术相关因素。对 PPC 组和非 PPC 组患者的临床资料进行比较,采用 t 检验或 χ 检验进行统计学分析。进一步采用二项逻辑回归分析识别 PPC 的潜在独立危险因素。

结果

本研究共纳入 445 例患者,其中 49 例(11%)发生 PPC,396 例(89%)未发生 PPC。老年患者择期结直肠手术后 PPC 发生的主要危险因素包括年龄较大(年龄≥75 岁)、ASA>II、高血压、心肌缺血、基础肺部疾病、剖腹手术、输血、术前血红蛋白<100 g/L 和白蛋白<35 g/L。剖腹手术(与腹腔镜手术相比)和 ASA>II 是 PPC 发生率增加的独立危险因素。

结论

择期结直肠手术应更加关注年龄较大和 ASA>II 的患者。选择腹腔镜手术、适当治疗高血压、心肌缺血、基础肺部疾病以及纠正贫血和营养状况,可以有效降低 PPC 的发生率。术前需要充分全面地评估与 PPC 相关的潜在危险因素。

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