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手术环境和患者相关因素在预测腹部手术后发生术后肺部并发症中的作用。

Role of surgical setting and patients-related factors in predicting the occurrence of postoperative pulmonary complications after abdominal surgery.

机构信息

Department of Anaesthesiology and Intensive Care, A. Gemelli University Hospital Foundation, Rome, Italy.

出版信息

Eur Rev Med Pharmacol Sci. 2018 Jan;22(2):547-550. doi: 10.26355/eurrev_201801_14208.

DOI:10.26355/eurrev_201801_14208
PMID:29424916
Abstract

OBJECTIVE

The aim of this retrospective study was to evaluate the role of surgical setting (urgent vs. elective) and approach (open vs. laparoscopic) in affecting postoperative pulmonary complications (PPCs) prevalence in patients undergoing abdominal surgery.

PATIENTS AND METHODS

After local Ethical Committee approval, 409 patients who had undergone abdominal surgery between January and December 2014 were included in the final analysis. PPCs were defined as the development of one of the following new findings: respiratory failure, pulmonary infection, aspiration pneumonia, pleural effusion, pneumothorax, atelectasis on chest X-ray, bronchospasm or un-planned urgent re-intubation.

RESULTS

PPCs prevalence was greater in urgent (33%) vs. elective setting (7%) (χ2 with Yates correction: 44; p=0.0001) and in open (6%) vs. laparoscopic approach (1.9%) (χ2 with Yates correction: 12; p=0.0006). PPCs occurrence was positively correlated with in-hospital mortality (Biserial Correlation r=0.37; p=0.0001). Logistic regression showed that urgent setting (p=0.000), Ariscat (Assess Respiratory Risk in Surgical Patients in Catalonia) score (p=0.004), and age (p=0.01) were predictors of PPCs. A cut-off of 23 for Ariscat score was also identified as determining factor for PPCs occurrence with 94% sensitivity and 29% specificity.

CONCLUSIONS

Patients undergoing abdominal surgery in an urgent setting were exposed to a higher risk of PPCs compared to patients scheduled for elective procedures. Ariscat score fitted with PPCs prevalence and older patients were exposed to a higher risk of PPCs. Prospective studies are needed to confirm these results.

摘要

目的

本回顾性研究旨在评估手术时机(紧急与择期)和手术入路(开放与腹腔镜)对行腹部手术患者术后肺部并发症(PPC)发生率的影响。

患者与方法

经当地伦理委员会批准,纳入 2014 年 1 月至 12 月期间行腹部手术的 409 例患者进行最终分析。PPC 定义为出现以下新发现之一:呼吸衰竭、肺部感染、吸入性肺炎、胸腔积液、气胸、胸片上的肺不张、支气管痉挛或计划外紧急重新插管。

结果

紧急手术(33%)较择期手术(7%)(经 Yates 校正的卡方检验:44;p=0.0001)和开放手术(6%)较腹腔镜手术(1.9%)(经 Yates 校正的卡方检验:12;p=0.0006)的 PPC 发生率更高。PPC 发生与住院死亡率呈正相关(双变量相关系数 r=0.37;p=0.0001)。Logistic 回归显示,紧急手术(p=0.000)、阿西卡特评分(Assess Respiratory Risk in Surgical Patients in Catalonia,p=0.004)和年龄(p=0.01)是 PPC 的预测因素。阿西卡特评分的截断值为 23 分,也被确定为 PPC 发生的决定因素,其敏感度为 94%,特异度为 29%。

结论

与择期手术相比,紧急手术患者发生 PPC 的风险更高。阿西卡特评分与 PPC 发生率相关,年龄较大的患者发生 PPC 的风险更高。需要前瞻性研究来证实这些结果。

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