Philipp H, Scholz D, Menzel G
Z Urol Nephrol. 1977 May;70(5):331-8.
263 examinations with the rosette-test with sheep erythrocytes and the rosette inhibition test with antilymphocyte globulin in 42 normal persons and 56 patients after transplantation of a kidney showed in 10 patients a significnat decrease of the rosette-forming T-lymphocytes in the peripheral blood under conditions of rejection. On the other hand the number of rosettes significantly increased in 4 patients. The valency of the rosette inhibition test for the rejection diagnostics is restricted by technical difficulties and wrong positive results (11%). The results are discussed on the basis of the receptor synthesis rates for sheep erythrocytes and of the electric superficial potentials of the T-lymphocytes and in relation to the HLA-A/B/C/D-system.