Wang K Y, Kimmey M B, Nyberg D A, Mack L A, Haggitt R C, Shuman W P, Franklin D W, Silverstein F E
Department of Radiology, University of Washington, Seattle 98104.
Radiology. 1987 Dec;165(3):827-9. doi: 10.1148/radiology.165.3.3317508.
Six normal and 16 neoplastic colorectal specimens were examined with 8.5-MHz ultrasound (US). An articulated system facilitated precise spatial correlation between US and histologic sections. Images were blindly interpreted and then compared with histologic results. All six normal specimen showed five distinct echo layers and were distinguished from neoplastic specimens by all the observers. The central echogenic layer, corresponding to the submucosa, is useful in determining the depth of origin of a neoplasm and the presence of submucosal invasion. US had an accuracy of 92.5% in demonstrating invasion of the submucosa and 77% for invasion of the muscularis externa. For mucosal neoplasms with invasion through the muscularis externa and extension into the subserosal tissues, nearly 90% of US interpretations were correct. High-frequency US may be useful in determining the depth of invasion of mucosal tumors with respect to the submucosa and in differentiating mucosal from extramural masses.
对6个正常结肠直肠标本和16个肿瘤性结肠直肠标本进行了8.5兆赫超声（US）检查。一个关节系统有助于实现超声与组织学切片之间精确的空间关联。图像由不知情的人员进行解读，然后与组织学结果进行比较。所有6个正常标本均显示出五个不同的回声层，所有观察者都能将其与肿瘤性标本区分开来。对应于黏膜下层的中央回声层，有助于确定肿瘤的起源深度以及黏膜下层浸润情况。超声在显示黏膜下层浸润方面的准确率为92.5%，在显示肌层浸润方面的准确率为77%。对于侵犯肌层并延伸至浆膜下组织的黏膜肿瘤，超声解读的正确率接近90%。高频超声可能有助于确定黏膜肿瘤相对于黏膜下层的浸润深度，并有助于区分黏膜内肿物与壁外肿物。
