Giovagnoni A, Misericordia M, Terilli F, Brunelli E, Contucci S, Bearzi I
Department of Radiology, NMR Center, Regional Hospital Torrette, University of Ancona, Italy.
Abdom Imaging. 1993 Fall;18(4):371-5. doi: 10.1007/BF00201786.
High-resolution magnetic resonance imaging (MRI) was used to study 16 resected rectosigmoid specimens of patients treated with total colectomy for severe ulcerative colitis (UC). Six normal colon specimens were also studied as a control group. Moreover, a parallel study of the pelvis of 24 patients with a proven diagnosis of UC was performed with the same MR system. Both in vitro and in vivo MRI findings [thickening and signal intensity (SI)] of the mural layers were qualitatively evaluated by two radiologists and compared with gross and microscopic aspects. In vitro results showed that MRI was able to identify all layers of the colonic wall. In particular in UC specimens, MRI identified thickening and the peculiar abnormal hyperintensity of the mucosal and submucosal layers on spin-echo (SE) T1-weighted images. In vivo results confirmed the high-signal intensity of the mucosal and submucosal layers. These findings were not observed in the control group in which the superficial layers appeared low in intensity on SE T1 images. Our preliminary experience suggests that MRI should be considered a new imaging modality for detecting UC colonic wall changes.
采用高分辨率磁共振成像（MRI）对16例因重症溃疡性结肠炎（UC）接受全结肠切除术患者的直肠乙状结肠切除标本进行研究。另外选取6例正常结肠标本作为对照组进行研究。此外，使用同一台MR系统对24例确诊为UC的患者的骨盆进行了一项平行研究。两名放射科医生对壁层的体外和体内MRI表现[增厚及信号强度（SI）]进行了定性评估，并与大体和微观表现进行了比较。体外结果显示，MRI能够识别结肠壁的所有层次。特别是在UC标本中，MRI在自旋回波（SE）T1加权图像上识别出黏膜层和黏膜下层增厚以及特有的异常高信号。体内结果证实了黏膜层和黏膜下层的高信号强度。在对照组的SE T1图像上，表层信号强度较低，未观察到这些表现。我们的初步经验表明，MRI应被视为检测UC结肠壁变化的一种新的成像方式。
