InBioS - PhytoSystems, Functional Genomics and Plant Molecular Imaging, University of Liège, 4000 Liège, Belgium.
BPMP, Univ. Montpellier, CNRS, INRA, Montpellier SupAgro, Montpellier, France.
J Exp Bot. 2021 Mar 17;72(6):2136-2153. doi: 10.1093/jxb/eraa483.
In plants, iron (Fe) transport and homeostasis are highly regulated processes. Fe deficiency or excess dramatically limits plant and algal productivity. Interestingly, complex and unexpected interconnections between Fe and various macro- and micronutrient homeostatic networks, supposedly maintaining general ionic equilibrium and balanced nutrition, are currently being uncovered. Although these interactions have profound consequences for our understanding of Fe homeostasis and its regulation, their molecular bases and biological significance remain poorly understood. Here, we review recent knowledge gained on how Fe interacts with micronutrient (e.g. zinc, manganese) and macronutrient (e.g. sulfur, phosphate) homeostasis, and on how these interactions affect Fe uptake and trafficking. Finally, we highlight the importance of developing an improved model of how Fe signaling pathways are integrated into functional networks to control plant growth and development in response to fluctuating environments.
在植物中，铁（Fe）的运输和稳态是高度调节的过程。Fe 的缺乏或过量极大地限制了植物和藻类的生产力。有趣的是，目前正在揭示 Fe 与各种宏量和微量营养稳态网络之间复杂且出乎意料的相互联系，这些网络据称可以维持一般的离子平衡和均衡的营养。尽管这些相互作用对我们理解 Fe 稳态及其调节具有深远的影响，但它们的分子基础和生物学意义仍知之甚少。在这里，我们回顾了最近关于 Fe 如何与微量元素（例如锌、锰）和大量元素（例如硫、磷）稳态相互作用的知识，以及这些相互作用如何影响 Fe 的吸收和运输。最后，我们强调了开发一种改进的模型的重要性，该模型可以将 Fe 信号通路整合到功能网络中，以控制植物生长和发育，以应对不断变化的环境。
