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应用放射免疫分析试剂盒对血管活性肠肽(VIP)在胰腺炎中的基础及临床评估

Fundamental and clinical evaluation of vasoactive intestinal peptide (VIP) in pancreatitis by radioimmunoassay kit.

作者信息

Uehara S, Nakamura T, Ihara K, Isogawa S, Hirayama A

机构信息

Department of Internal Medicine, Tonan Hospital, Sapporo-shi, Japan.

出版信息

Radioisotopes. 1987 Jul;36(7):355-8. doi: 10.3769/radioisotopes.36.7_355.

DOI:10.3769/radioisotopes.36.7_355
PMID:3317528
Abstract

Plasma vasoactive intestinal peptide (VIP) concentrations of normal individuals and patients with pancreatitis were studied using a VIP RIA kit. The inter-assay and intra-assay variation of this kit were between 2.1 and 9.4%. The VIP levels increased in the acute phase of acute pancreatitis and patients with chronic pancreatitis. The VIP concentration increased during the first 30 min of glucose tolerance test, but this increase was much smaller than that in insulin. These results suggest that this kit is useful for physiologic and pathologic changes in the VIP level.

摘要

使用血管活性肠肽放射免疫分析试剂盒研究了正常个体和胰腺炎患者的血浆血管活性肠肽(VIP)浓度。该试剂盒的批间和批内变异在2.1%至9.4%之间。急性胰腺炎急性期和慢性胰腺炎患者的VIP水平升高。在葡萄糖耐量试验的前30分钟内,VIP浓度升高,但这种升高远小于胰岛素的升高。这些结果表明,该试剂盒可用于检测VIP水平的生理和病理变化。

相似文献

1
Fundamental and clinical evaluation of vasoactive intestinal peptide (VIP) in pancreatitis by radioimmunoassay kit.应用放射免疫分析试剂盒对血管活性肠肽(VIP)在胰腺炎中的基础及临床评估
Radioisotopes. 1987 Jul;36(7):355-8. doi: 10.3769/radioisotopes.36.7_355.
2
[Vasoactive intestinal peptide (VIP) in the Verner-Morrison syndrome (author's transl)].韦纳-莫里森综合征中的血管活性肠肽(作者译)
Nouv Presse Med. 1979 Apr 21;8(18):1505-8.
3
Verner-Morrison syndrome and vasoactive intestinal polypeptide (VIP).韦纳-莫里森综合征与血管活性肠肽(VIP)。
Scand J Gastroenterol Suppl. 1979;53:57-60.
4
Vasoative intestinal peptide and the watery diarrhea syndrome.血管活性肠肽与水样腹泻综合征
Ann Surg. 1978 Apr;187(4):411-6. doi: 10.1097/00000658-197804000-00012.
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Long-term pancreatic duct occlusion impairs the entero-insular axis in the dog--failure of plasma VIP to respond as "incretin".长期胰腺导管阻塞会损害犬的肠-胰岛轴——血浆血管活性肠肽无法作为“肠促胰岛素”做出反应。
Peptides. 1984 Mar-Apr;5(2):445-50. doi: 10.1016/0196-9781(84)90252-3.
6
Gastrointestinal dysmotility in patients with acute pancreatitis.急性胰腺炎患者的胃肠动力障碍
J Gastroenterol Hepatol. 2003 Jan;18(1):57-62. doi: 10.1046/j.1440-1746.2003.02898.x.
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Clinical and hormonal aspects of the watery diarrhea-hypokalemia-achlorhydria (WDHA) syndrome due to vasoactive intestinal polypeptide (VIP)-producing tumor.由产生血管活性肠肽(VIP)的肿瘤引起的水样腹泻-低钾血症-无胃酸(WDHA)综合征的临床和激素方面
Endocrinol Jpn. 1980 Dec;27 Suppl 1:79-86. doi: 10.1507/endocrj1954.27.supplement_79.
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Cosecretion of peptide histidine methionine (PHM) and vasoactive intestinal peptide (VIP) in patients with VIP-producing tumors.产生血管活性肠肽(VIP)的肿瘤患者中肽组氨酸蛋氨酸(PHM)与血管活性肠肽(VIP)的共同分泌。
Peptides. 1986 Sep-Oct;7(5):717-21. doi: 10.1016/0196-9781(86)90084-7.
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Peptide histidine-methionine immunoreactivity in plasma and tissue from patients with vasoactive intestinal peptide-secreting tumors and watery diarrhea syndrome.
J Clin Endocrinol Metab. 1987 Jan;64(1):131-9. doi: 10.1210/jcem-64-1-131.
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Serum insulin levels in patients with chronic pancreatitis.慢性胰腺炎患者的血清胰岛素水平。
Am J Surg. 1970 Feb;119(2):171-6. doi: 10.1016/0002-9610(70)90029-2.

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