Urology and Nephrology Center, Mansoura University, Mansoura, Egypt.
Int Urol Nephrol. 2021 Apr;53(4):635-640. doi: 10.1007/s11255-020-02707-4. Epub 2020 Nov 11.
The use of non-intubated uroflowmetry, PVR, prostate volume, and I-PSS are the most commonly used tools for the evaluation of patients with BPH. In this prospective study, we elucidated the correlation between BOO as rated by pressure-flow study in men with LUTS attributed to BPH and those parameters.
Over a period of 2 years 460 men above the age of 45 years old (mean age 60.46 ± 9.4) were prospectively included in this study. Symptoms were evaluated using the International Prostate Symptom Score, and digital rectal examination, prostate-specific antigen, and transrectal ultrasound were done. The urodynamic evaluation included uroflowmetry, filling cystometry, and voiding cystometry with the plotting of pressure-flow study according to Lin-PURR (Schäfer's nomogram). The correlation coefficient was calculated between these variables.
The correlation of other objective parameters with total score was not much better. The Spearman's correlation coefficient were - 0.09, 0.07 and - 0.1 for prostate weight, post voiding residual urine and maximum free flow rate respectively. Correlations between Schäfer's grade and Q, PVR and prostate volume were found to be weak to fair correlation (r values were - 0.4, 0.18, and 0.39 respectively).
Objective non-invasive parameters most commonly used in the evaluation of men with LUTS attributed to BPH have limited correlation with obstruction, as diagnosed by pressure flow nomogram.
非插管尿流率、PVR、前列腺体积和 I-PSS 是评估 BPH 患者最常用的工具。在这项前瞻性研究中，我们阐明了压力-流研究中评估的 BOO 与这些参数之间的相关性。
在 2 年的时间里，前瞻性地纳入了 460 名年龄在 45 岁以上（平均年龄 60.46±9.4 岁）的男性。使用国际前列腺症状评分和直肠指检、前列腺特异性抗原和经直肠超声评估症状。尿动力学评估包括尿流率、充盈膀胱测压和排空膀胱测压，并根据 Lin-PURR（Schäfer 列线图）绘制压力-流研究图。计算这些变量之间的相关系数。
其他客观参数与总评分的相关性也不是很好。前列腺重量、残余尿量和最大自由流率的 Spearman 相关系数分别为-0.09、0.07 和-0.1。发现 Schäfer 分级与 Qmax、PVR 和前列腺体积之间存在弱至中度相关性（r 值分别为-0.4、0.18 和 0.39）。
在评估 LUTS 归因于 BPH 的男性时，最常用的客观无创参数与压力流列线图诊断的梗阻相关性有限。
