Chen Wei, Chen Yuanyuan, Geng Yue, Lin Naier, Luo Siqi, Wang Zhengyue, Yu Sihui, Sha Yan
Shanghai Institute of Medical Imaging, Fudan University, Shanghai, China.
Department of Radiology, Zhongshan Hospital of Fudan University, Shanghai, China.
Acta Otolaryngol. 2021 Feb;141(2):117-121. doi: 10.1080/00016489.2020.1843071. Epub 2020 Nov 12.
Intravenous gadolinium injection (IV-method) can be used to visualize endolymphatic hydrops.
AIMS/OBJECTIVES: This study was designed to use a three-dimensional inversion-recovery sequence with real reconstruction (3 D-real IR) sequence 4 h after the IV-method, images of the perilymph space were scored for endolymphatic hydrops in cases of suspected Meniere's disease (MD) in children to investigate its diagnostic value of MD in children.
We collected 28 suspected MD children aged ≤17 years old, all of whom underwent the IV-method. After 4 h, inner ear 3 D-real IR magnetic resonance imaging (MRI) was performed and results were analyzed.
Gadolinium contrast agent was seen distributed in the perilymphatic space with perilymphatic enhancement on 3 D-real IR MRI, allowing differentiation between the perilymphatic and endolymphatic spaces. Based on perilymph MRI diagnostic scoring, 64.3% (18/28) of the patients were categorized as having endolymphatic hydrops, who were followed and eventually diagnosed with confirmed MDs.
Suspected MD children should undergo gadolinium-enhanced examinations of the inner ear while taking dynamic audiology examinations for the confirmed diagnosis.
静脉注射钆剂（静脉注射法）可用于显示内淋巴积水。
本研究旨在采用三维反转恢复序列与实时重建（3D-实时IR）序列，在静脉注射法后4小时，对疑似儿童梅尼埃病（MD）患者的外淋巴间隙图像进行内淋巴积水评分，以研究其对儿童MD的诊断价值。
我们收集了28例年龄≤17岁的疑似MD儿童，所有患者均接受了静脉注射法。4小时后，进行内耳3D-实时IR磁共振成像（MRI）并分析结果。
在3D-实时IR MRI上可见钆造影剂分布在外淋巴间隙，外淋巴强化，从而能够区分外淋巴间隙和内淋巴间隙。根据外淋巴MRI诊断评分，64.3%（18/28）的患者被归类为有内淋巴积水，对其进行随访并最终确诊为MD。
疑似MD的儿童应接受内耳钆增强检查，同时进行动态听力学检查以确诊。
