Fundació Docència i Recerca Mútua de Terrassa, Terrassa, Barcelona, Spain.
Movement disorders Unit, Department of Neurology, Memory Disorders Unit, Hospital Universitari Mútua de Terrassa, Terrassa, Barcelona, Spain.
J Neuroeng Rehabil. 2020 Nov 11;17(1):149. doi: 10.1186/s12984-020-00770-7.
Accurate assessment of balance and gait is necessary to monitor the clinical progress of Parkinson's disease (PD). Conventional clinical scales can be biased and have limited accuracy. Novel interactive devices are potentially useful to detect subtle posture or gait-related impairments.
Posturographic and single and dual-task gait assessments were performed to 54 individuals with PD and 43 healthy controls with the Wii Balance Board and the Kinect v2 and the, respectively. Individuals with PD were also assessed with the Tinetti Performance Oriented Mobility Assessment, the Functional Gait Assessment and the 10-m Walking Test. The influence of demographic and clinical variables on the performance in the instrumented posturographic and gait tests, the sensitivity of these tests to the clinical condition and phenotypes, and their convergent validity with clinical scales were investigated.
Individuals with PD in H&Y I and I.5 stages showed similar performance to controls. The greatest differences in posture and gait were found between subjects in H&Y II.5 and H&Y I-I.5 stage, as well as controls. Dual-tasking enhanced the differences among all groups in gait parameters. Akinetic/rigid phenotype showed worse postural control and gait than other phenotypes. High significant correlations were found between the limits of stability and most of gait parameters with the clinical scales.
Low-cost devices showed potential to objectively quantify posture and gait in established PD (H&Y ≥ II). Dual-tasking gait evaluation was more sensitive to detect differences among PD stages and compared to controls than free gait. Gait and posture were more impaired in akinetic/rigid PD.
准确评估平衡和步态对于监测帕金森病（PD）的临床进展是必要的。传统的临床量表可能存在偏差且准确性有限。新型交互设备可能有助于检测细微的姿势或与步态相关的障碍。
使用 Wii Balance Board 和 Kinect v2 对 54 名 PD 患者和 43 名健康对照者进行了足印图和单任务及双任务步态评估。PD 患者还接受了 Tinetti 表现型定向移动评估、功能性步态评估和 10 米步行测试。研究了仪器化足印图和步态测试中与人口统计学和临床变量相关的表现、这些测试对临床状况和表型的敏感性以及与临床量表的收敛效度。
处于 H&Y I 和 I.5 期的 PD 患者与对照组的表现相似。在 H&Y II.5 和 H&Y I-I.5 期的患者以及对照组之间，姿势和步态的差异最大。双任务步态测试增加了所有组之间步态参数的差异。无动性/僵硬表型的姿势控制和步态比其他表型差。稳定性极限与大多数步态参数与临床量表之间存在高度显著相关性。
低成本设备具有客观量化已确诊 PD（H&Y≥II）患者的姿势和步态的潜力。与自由步态相比，双任务步态评估更能敏感地检测出 PD 各阶段之间的差异，以及与对照组之间的差异。无动性/僵硬 PD 的步态和姿势更差。
