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[鼠疫微生物EV株与豚鼠脾细胞体外相互作用时的超微结构变化]

[Ultrastructural changes in plague microbes, strain EV, and splenic cells of guinea pigs in their interaction in vitro].

作者信息

Isupov I V, Kenig E E, Zhukov V G, Konstantinova N S, Zemtsova I N

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1977 May(5):55-8.

PMID:331769
Abstract

Dilatation of the endoplasmic reticulum cavities, an increase in the number of ribosomes near bacteria, deformation of mitochondria and coarsening of cristae were revealed in phagocytosis of Past. pestis, strain EV, by reticular cells in the tissue culture of the spleen of intact guinea pigs. Lipophanerous "reticular" inclusions were found in the differentiated reticular cells of the infected cultures. In the reticular cell cytoplasma besides the intact bacteria there were revealed Past. pestis at the initial stages of involution.

摘要

在未感染豚鼠脾脏组织培养中,网状细胞对鼠疫杆菌EV株进行吞噬作用时,可见内质网腔扩张、细菌附近核糖体数量增加、线粒体变形以及嵴增粗。在受感染培养物的分化网状细胞中发现了脂质性“网状”包涵体。在网状细胞胞质中,除了完整细菌外,还发现了处于退化初期的鼠疫杆菌。

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