Patel Ravi C, Kubicki Shelby L, Cohen Philip R, MacFarlane Deborah F
Dermatology, MD Anderson Cancer Center, Houston, USA.
Dermatology, University of Texas McGovern Medical School, Houston, USA.
Cureus. 2020 Oct 9;12(10):e10866. doi: 10.7759/cureus.10866.
Facial swelling has several etiologies. In patients with head and neck malignancies, this can include primary disease progression or iatrogenic causes. A 66-year-old man presented with increased facial swelling and erythema for 18 months. He had a history of baseline postoperative facial lymphedema following head and neck surgery and radiotherapy for desmoplastic melanoma approximately 20 years ago. However, his facial edema acutely worsened 18 months prior to presentation. A medication review revealed that he was regularly taking melatonin for the past two years. Approximately two weeks after cessation of melatonin therapy, the patient's facial appearance returned to baseline. In conclusion, it is important for clinicians to perform a thorough medication review for patients with facial swelling and erythema.
面部肿胀有多种病因。对于头颈部恶性肿瘤患者，这可能包括原发性疾病进展或医源性原因。一名66岁男性出现面部肿胀和红斑加重18个月。他大约20年前因促纤维增生性黑色素瘤接受头颈部手术和放疗后有基线术后面部淋巴水肿病史。然而，在就诊前18个月，他的面部水肿急剧加重。药物审查发现，他在过去两年中一直在规律服用褪黑素。在停止褪黑素治疗约两周后，患者的面部外观恢复到基线水平。总之，临床医生对有面部肿胀和红斑的患者进行全面的药物审查很重要。
