Awad Dana, Kousa Omar, Essa Amr, Kuniyoshi Jason, Kousa Hamza, Qasim Abdallah, Andukuri Venkata, Kassim Thamer
Internal Medicine Residency, Creighton University, Omaha, NE, USA.
Medical Student, Creighton University, Omaha, NE, USA.
AME Case Rep. 2020 Oct 30;4:23. doi: 10.21037/acr-20-72. eCollection 2020.
Cerebrovascular disease is the second leading cause of death in the United States in adults aged 65 years and older and is most commonly caused by atherosclerosis. More so, cryptogenic strokes account for one-third of all ischemic strokes. At the same time, iron deficiency anemia is prevalent worldwide and mostly affects females of childbearing age. Here we report a case of a 42-year-old female who presented with symptoms of acute ischemic stroke and was found to have severe iron deficiency anemia. After prompt investigation of other secondary causes, it was determined that her stroke was likely secondary to her iron deficiency anemia. Upon review of the literature, a few case reports showed an association between iron deficiency anemia and strokes in the adult population, but little evidence exists supporting a direct relationship between the two entities. In this case, we aim to evaluate the complex relationship between iron deficiency anemia and stroke and to define a new potential cause of ischemic stroke, which would have been considered earlier as cryptogenic. However, further studies in the future are warranted to validate our observation.
在美国，脑血管疾病是65岁及以上成年人的第二大死因，最常见的病因是动脉粥样硬化。此外，不明原因的中风占所有缺血性中风的三分之一。与此同时，缺铁性贫血在全球范围内普遍存在，主要影响育龄女性。在此，我们报告一例42岁女性，她出现急性缺血性中风症状，经检查发现患有严重缺铁性贫血。在迅速排查其他继发原因后，确定她的中风可能继发于缺铁性贫血。查阅文献发现，少数病例报告显示缺铁性贫血与成年人群中风之间存在关联，但几乎没有证据支持两者之间存在直接关系。在本病例中，我们旨在评估缺铁性贫血与中风之间的复杂关系，并确定缺血性中风的一个新的潜在病因，该病因原本可能被视为不明原因。然而，未来有必要进行进一步研究以验证我们的观察结果。
