Department of Experimental Medicine, Forensic Toxicology Unit, University of Campania 'L. Vanvitelli', Naples 80138, Italy.
J Anal Toxicol. 2022 Feb 14;46(1):e16-e20. doi: 10.1093/jat/bkaa174.
Drug-facilitated sexual assault (DFSA) cases are pretty common in forensic toxicology. In this case report, a 56-year-old female tourist claimed to have been sexually assaulted by five men after having had a drug-spiked alcoholic drink. Urine samples were collected at 38, 44 and 45 h after the alleged rape. After 7 months, hair strands (28 cm in length) were also sampled to perform the segmental hair testing. The urine samples and decontaminated hair segments were tested for different groups of basic, acidic and neutral substances (γ-hydroxybutyrate or GHB, Z-drugs, barbiturates, benzodiazepines, hypnotics, antipsychotics and drugs of abuse). Gas chromatography-mass spectrometry and liquid chromatography-tandem mass spectrometry methods were applied for the qualitative and quantitative analyses. Toxicological analyses performed on the urine samples showed inconclusive findings. Zolpidem, flunitrazepam and oxazepam were detected in the hair segments corresponding to the time frame of the alleged assault. The endogenous levels of GHB were detected along the hair shaft. No drugs were detected in the proximal and distal hair segments or in washing solutions. This DFSA case demonstrated that the segmental toxicological analysis of hair, even when performed 7 months after the sexual assault, can provide evidence consistent with a single exposure to psychoactive drugs, at the time of the offense.
药物辅助性性侵犯（DFSA）案件在法医毒理学中相当常见。在本案例报告中，一名 56 岁的女游客声称在饮用了掺有药物的酒精饮料后遭到五名男子的性侵犯。在据称的强奸后 38、44 和 45 小时收集了尿液样本。7 个月后，还采集了 28 厘米长的头发样本进行分段毛发检测。对尿液样本和去污染的头发段进行了不同组别的基本、酸性和中性物质（γ-羟基丁酸或 GHB、Z 药物、巴比妥类药物、苯二氮䓬类药物、催眠药、抗精神病药和滥用药物）的检测。应用气相色谱-质谱法和液相色谱-串联质谱法进行定性和定量分析。尿液样本的毒理学分析结果没有明确结论。在头发段中检测到唑吡坦、氟硝西泮和奥沙西泮，这些物质与据称的攻击时间相对应。在头发轴上检测到内源性 GHB 水平。在近端和远端头发段或洗涤溶液中均未检测到药物。这个 DFSA 案例表明，即使在性侵犯发生 7 个月后进行分段毒理学毛发分析，也可以提供与单一接触致幻药物一致的证据，这些药物是在犯罪时摄入的。
