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[风险因素对肾移植术后早期及长期局部结果的影响]

[Effect of risk factors on early and long-term regional results following kidney transplantation].

作者信息

Piza F, Mühlbacher F, Schemper M

机构信息

Abteilung für Organtransplantation, I. Chirurgischen Universitätsklinik, Wien.

出版信息

Wien Klin Wochenschr. 1987 Oct 9;99(19):665-72.

PMID:3318146
Abstract

An observational study by multifactorial statistical analysis was undertaken on 785 kidney transplants. Risk factors in first transplants for primary non-function are cold ischaemic time, donor centre and acute rejection, with a non-function rate of 8% and a delayed function of 37%. Risk factors for transplant survival are bad match, no preoperative transfusions, age of recipient below 40 years, male sex, diabetes, conventional immunosuppressive therapy and cadaver donors. Donor centre and delayed primary function have no influence on long-term kidney function. The analysis revealed additive effects of various risk factors. This has to be taken into account in recipient-selecting policy.

摘要

对785例肾移植进行了多因素统计分析的观察性研究。首次移植原发性无功能的危险因素为冷缺血时间、供体中心和急性排斥反应,无功能率为8%,延迟功能率为37%。移植存活的危险因素为配型不佳、术前未输血、受者年龄低于40岁、男性、糖尿病、传统免疫抑制治疗和尸体供体。供体中心和原发性延迟功能对长期肾功能无影响。分析显示了各种危险因素的累加效应。在受者选择策略中必须考虑到这一点。

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