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性交后甾体激素阻断法。

Postcoital interception with steroids.

作者信息

van Santen M R, Haspels A A

机构信息

State University Hospital, Dept. Obst. & Gyn., Utrecht, The Netherlands.

出版信息

Wien Med Wochenschr. 1987 Oct 15;137(18-19):465-70.

PMID:3318160
Abstract

At present there is a high demand for PCI. The psychological distress experienced by women after unprotected intercourse while awaiting the onset of her next menses could be avoided with effective postcoital treatment. As demonstrated in countries with good health services, the availability of PCI leads to low abortion rates. PCI is designed for use as an emergency method after unprotected intercourse as an isolated incident. Women who have frequent intercourse however, do better to use a regular, very effective, method of contraception such as a combined oral contraceptive. Postcoital progestagens can well be used in infrequent intercourse since they are to be taken after each coitus, if applicable several times a month. Such use however leads to menstrual cycle disturbances and irregular bleedings. The estrogen-only and the estrogen-progestin combination are recommended, but need to be given within 2 or 3 days after the event of unprotected intercourse, preferably periovulatory. The latest development of the anti-progestins as a morning-after pill is promising. Taken from day 27 through 30 of the menstrual cycle it induces menstruation at the expected day. Side effects are minimal and the efficacy is good. Because of the imperfectness of PCI to prevent all pregnancies, sofar this regimen cannot be recommended for monthly use and does not replace regular oral contraceptives. PCI has a definite place in family-planning and fertility regulation. Since different methods are available today careful assessment of individual needs can help to decide for the best suitable method for the individual person.

摘要

目前对性交后避孕(PCI)的需求很高。在等待下次月经来潮期间发生无保护性交的女性所经历的心理困扰,可以通过有效的性交后治疗来避免。正如在医疗服务良好的国家所表明的那样,PCI的可及性导致低堕胎率。PCI被设计用作无保护性交这一孤立事件后的紧急方法。然而,性交频繁的女性最好使用常规、非常有效的避孕方法,如复方口服避孕药。性交后使用孕激素适用于性交不频繁的情况,因为每次性交后都要服用,如果适用的话,一个月可能要服用几次。然而,这种使用会导致月经周期紊乱和不规则出血。推荐使用仅含雌激素和雌激素 - 孕激素组合的药物,但需要在无保护性交事件发生后的2或3天内服用,最好是在排卵期前后。抗孕激素作为事后避孕药的最新进展很有前景。在月经周期的第27天至30天服用,它会在预期的日子诱导月经来潮。副作用最小,效果良好。由于PCI预防所有妊娠的不完善性,到目前为止,这种方案不推荐每月使用,也不能替代常规口服避孕药。PCI在计划生育和生育调节中具有明确的地位。由于目前有不同的方法,仔细评估个人需求有助于为个人决定最合适的方法。

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