Köhler G, Göretzlehner G
Zentralbl Gynakol. 1984;106(17):1173-81.
Large doses of estrogens employed for postcoital contraception have definitely been shown to be effective, but estrogens used in such high doses would result in a high incidence of side-effects. Therefore this method should be reserved for the occasional emergency. Postcoital estrogen-progestogen-combination is suitable for women exposed to an isolated act of intercourse in midcycle. The advantage of this method is the possibility of a delayed administration after intercourse. Progestogens alone can be used after each coital exposure. One of the most frequent problems is the alteration of the menstrual pattern. Continued use can be recommended for women with occasional intercourse in cycle. Possible mechanisms of action of steroidal postcoital contraceptives are discussed involving problems of this contraceptive method.
大剂量雌激素用于性交后避孕已被明确证明是有效的，但如此高剂量使用雌激素会导致副作用发生率很高。因此，这种方法应仅用于偶尔的紧急情况。性交后雌激素 - 孕激素联合用药适用于在月经周期中期有单次性交的女性。这种方法的优点是性交后可以延迟给药。每次性交后都可以单独使用孕激素。最常见的问题之一是月经模式的改变。对于月经周期中有偶尔性交的女性，可以建议持续使用。文中讨论了甾体类性交后避孕药可能的作用机制以及这种避孕方法存在的问题。
