Lee Song Mi, Kang Byung-Jae, Lee Sungin, Kim Wan Hee
Department of Veterinary Clinical Sciences, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul 08826, Korea.
Animals (Basel). 2020 Nov 9;10(11):2069. doi: 10.3390/ani10112069.
Collecting blood from an indwelling arterial catheter may reduce stress from repeated venipuncture in patients requiring serial monitoring, but the use of arterial blood for hematological and biochemical testing remains understudied. Here, we compared hematological and biochemical results of arterial and venous blood and evaluated their clinical interchangeability. Blood samples from dogs who had recovered from anesthesia, collected by both arterial catheterization and venipuncture, were analyzed. To assess clinical acceptance between paired samples, the limit of agreement between the values derived from the arterial and venous blood samples was compared with the allowable total error (TEa) recommended for each parameter. We found no significant differences between the arterial and venous sample results for red/white blood cell and platelet counts and hematocrit, blood urea nitrogen, phosphate, total protein, albumin, alanine aminotransferase, aspartate aminotransferase, alkaline phosphatase, gamma-glutamyl transpeptidase, total bilirubin, sodium, potassium, and chloride levels, whereas hemoglobin, glucose, creatinine, and calcium levels differed significantly ( < 0.05). Moreover, only gamma-glutamyl transpeptidase and potassium exceeded the recommended TEa. Hematological and biochemical results derived from venous and arterial blood samples are clinically interchangeable in post-anesthetic dogs, with the exception of gamma-glutamyl transpeptidase and potassium; thus, these values should be used with caution.
从留置动脉导管采集血液可能会减轻需要连续监测的患者因反复静脉穿刺带来的压力，但动脉血用于血液学和生化检测的情况仍研究不足。在此，我们比较了动脉血和静脉血的血液学及生化结果，并评估了它们在临床上的可互换性。对通过动脉插管和静脉穿刺采集的、已从麻醉中恢复的犬只的血样进行了分析。为评估配对样本之间的临床可接受性，将动脉血和静脉血样本所得值之间的一致性界限与每个参数推荐的允许总误差（TEa）进行了比较。我们发现，红细胞/白细胞计数、血小板计数、血细胞比容、血尿素氮、磷酸盐、总蛋白、白蛋白、丙氨酸氨基转移酶、天冬氨酸氨基转移酶、碱性磷酸酶、γ-谷氨酰转肽酶、总胆红素、钠、钾和氯水平在动脉血和静脉血样本结果之间无显著差异，而血红蛋白、葡萄糖、肌酐和钙水平存在显著差异（<0.05）。此外，只有γ-谷氨酰转肽酶和钾超过了推荐的TEa。除γ-谷氨酰转肽酶和钾外，麻醉后犬只静脉血和动脉血样本的血液学和生化结果在临床上可互换；因此，使用这些值时应谨慎。
