Michigan Medicine, Department of Pediatrics, Division of Pediatric Pulmonary Medicine, L2221 Women's Hospital, 1500 E. Medical Center Dr., SPC 5212, Ann Arbor, MI 48109-5212, USA.
Michigan Medicine, Department of Pediatrics, Division of Pediatric Pulmonary Medicine, L2221 Women's Hospital, 1500 E. Medical Center Dr., SPC 5212, Ann Arbor, MI 48109-5212, USA.
Clin Nutr ESPEN. 2020 Dec;40:336-339. doi: 10.1016/j.clnesp.2020.08.006. Epub 2020 Aug 29.
Malnutrition is associated with Cystic Fibrosis (CF) disease progression. That contributes to decreased lung function, poor quality of life, and increased morbidity and mortality. Appetite stimulants (AS) have been used to help increase caloric intake. When caloric intake is inadequate, gastrostomy tube (GT) feeding is offered and has shown to improve weight gain. In some patients, both AS and GT placement might not be adequate to insure weight gain. That could be due to the underlying psychopathological issues like anxiety and depression that are common in CF.
To address malnutrition in CF.
Since increasing oral caloric intake was inadequate to improve weight gain. AS and GT feeding were discussed and offered. AS was started, but was not used regularly. However, GT was still needed to improve weight gain. Because of patient's hesitations, ongoing psychological counseling was done to help patient accept the intervention.
Addressing patient's depression and anxiety and the failure to gain adequate weight at the same time helped improving patient's nutritional status.
The presented case report demonstrates the improvement in weight gain and body mass index in a CF patient after addressing both the patient's psychological needs and increasing caloric intake through gastrostomy tube feeding.
营养不良与囊性纤维化(CF)疾病进展有关。这会导致肺功能下降、生活质量下降,以及发病率和死亡率增加。食欲刺激剂(AS)已被用于帮助增加热量摄入。当热量摄入不足时,会提供胃造口管(GT)喂养,并已显示出可改善体重增加。在某些患者中,食欲刺激剂和 GT 放置可能不足以确保体重增加。这可能是由于焦虑和抑郁等潜在的心理病理问题在 CF 中很常见。
解决 CF 中的营养不良问题。
由于增加口服热量摄入不足以改善体重增加,因此讨论并提供了食欲刺激剂和 GT 喂养。开始使用食欲刺激剂,但未定期使用。然而,仍需要 GT 来改善体重增加。由于患者的犹豫,正在进行持续的心理咨询,以帮助患者接受干预。
同时解决患者的抑郁和焦虑问题以及未能获得足够的体重有助于改善患者的营养状况。
本病例报告表明,在解决患者的心理需求和通过胃造口管喂养增加热量摄入的同时,囊性纤维化患者的体重增加和体重指数得到改善。