Gomes J A, Winters S L, Stewart D, Targonski A, Barreca P
Department of Medicine, Mount Sinai School of Medicine, City University of New York, New York.
Am J Cardiol. 1987 Dec 1;60(16):1290-8. doi: 10.1016/0002-9149(87)90610-2.
The optimal bandpass filter for signal averaging of the surface QRS complex to detect late potentials is undefined. A study was conducted in 87 patients; 25 (mean age 34 +/- 10 years) were normal (group I), 29 (60 +/- 20 years) had organic heart disease without ventricular tachycardia (group II) and 33 (62 +/- 15 years) had sustained ventricular tachycardia (group III). In all patients signal-averaged electrocardiography (200 beats) was performed using a sharp, bidirectional filter and data analyzed using the following 7 high-pass filter settings: 10, 15, 20, 25, 40, 80 and 100 Hz. For each filter the duration of the signal-averaged QRS complex, the low-amplitude signals of less than 40 microV and the root-mean-square voltage of the terminal 40 ms (RMS-40) were determined. Normal values for each filter were determined from group I patients. In all 3 groups, quantitative signal-averaged variables were filter dependent. There was a progressive and marked decrease in RMS-40 and a progressive and marked increase in low-amplitude signal duration as the high-pass filtering was increased from 10 to 100 Hz. In contrast, high-pass, filter-dependent changes in signal-averaged QRS duration were less marked. The sensitivity and specificity for each filter using RMS-40 as the index of late potentials in separating group III patients from group II patients were: 10 Hz-64% and 52%; 15 Hz-57% and 72%; 20 Hz-57% and 76%; 25 Hz-42% and 90%; 40 Hz-61% and 83%; 80 Hz-88% and 69%; and 100 Hz-79% and 62%, respectively.(ABSTRACT TRUNCATED AT 250 WORDS)
用于体表QRS波群信号平均以检测晚电位的最佳带通滤波器尚未明确。对87例患者进行了一项研究；25例（平均年龄34±10岁）为正常者（I组），29例（60±20岁）有器质性心脏病但无室性心动过速（II组），33例（62±15岁）有持续性室性心动过速（III组）。对所有患者使用尖锐的双向滤波器进行信号平均心电图检查（200次心跳），并使用以下7种高通滤波器设置分析数据：10、15、20、25、40、80和100Hz。对于每个滤波器，测定信号平均QRS波群的持续时间、小于40微伏的低幅信号以及终末40毫秒的均方根电压（RMS-40）。从I组患者确定每个滤波器的正常值。在所有3组中，定量信号平均变量依赖于滤波器。随着高通滤波从10Hz增加到100Hz，RMS-40逐渐显著降低，低幅信号持续时间逐渐显著增加。相比之下，信号平均QRS持续时间的高通滤波器依赖性变化不太明显。以RMS-40作为晚电位指标，在将III组患者与II组患者分开时，每个滤波器的敏感性和特异性分别为：10Hz-64%和52%；15Hz-57%和72%；20Hz-57%和76%；25Hz-42%和90%；40Hz-61%和83%；80Hz-88%和69%；100Hz-79%和62%。（摘要截断于250字）
