Department of Medicine, Stanford University, Stanford, California, USA.
Division of Cardiovascular Medicine, Department of Medicine, Stanford Cardiovascular Institute, Stanford University, Stanford, California, USA.
JACC Cardiovasc Interv. 2021 Feb 8;14(3):292-300. doi: 10.1016/j.jcin.2020.10.015. Epub 2020 Nov 9.
The aim of this study was to explore characteristics and outcomes of patients undergoing elective percutaneous coronary intervention (PCI) in ambulatory surgery centers (ASCs).
Little is known about patients who underwent ASC PCI before Medicare reimbursement was instituted in 2020.
Using commercial insurance claims from MarketScan, adults who underwent hospital outpatient department (HOPD) or ASC PCI for stable ischemic heart disease from 2007 to 2016 were studied. Propensity score analysis was used to measure the association between treatment setting and the primary composite outcome of 30-day myocardial infarction, bleeding complications, and hospital admission.
The unmatched sample consisted of 95,492 HOPD and 849 ASC PCIs. Patients who underwent ASC PCI were more likely to be younger than 65 years, to live in the southern United States, and to have managed or consumer-driven health insurance. ASC PCI was also associated with decreased fractional flow reserve utilization (odds ratio [OR]: 0.31; 95% confidence interval [CI]: 0.20 to 0.48; p < 0.001). In unmatched, multivariate analysis, ASC PCI was associated with increased odds of the primary outcome (OR: 1.25; 95% CI: 1.01 to 1.56; p = 0.039) and bleeding complications (OR: 1.80; 95% CI: 1.11 to 2.90; p = 0.016). In propensity-matched analysis, ASC PCI was not associated with the primary outcome (OR: 1.23; 95% CI: 0.94 to 1.60; p = 0.124) but was significantly associated with increased bleeding complications (OR: 2.49; 95% CI: 1.25 to 4.95; p = 0.009).
Commercially insured patients undergoing ASC PCI were less likely to undergo fractional flow reserve testing and had higher odds of bleeding complications than HOPD-treated patients. Further study is warranted as Medicare ASC PCI volume increases.
本研究旨在探讨在门诊手术中心(ASC)行择期经皮冠状动脉介入治疗(PCI)的患者的特征和结局。
在 2020 年医疗保险报销制度实施之前,关于在 ASC 行 PCI 的患者知之甚少。
利用 MarketScan 的商业保险理赔数据,对 2007 年至 2016 年期间因稳定型缺血性心脏病在医院门诊(HOPD)或 ASC 行 PCI 的成年人进行研究。采用倾向评分分析衡量治疗场所与 30 天内心肌梗死、出血并发症和住院的主要复合结局之间的关联。
未匹配样本包括 95492 例 HOPD 和 849 例 ASC PCI。行 ASC PCI 的患者更有可能年龄小于 65 岁,居住在美国南部,并且拥有管理式或消费者驱动型医疗保险。ASC PCI 还与减少血流储备分数(FRF)的使用相关(比值比 [OR]:0.31;95%置信区间 [CI]:0.20 至 0.48;p<0.001)。在未匹配的多变量分析中,ASC PCI 与主要结局的发生几率增加相关(OR:1.25;95%CI:1.01 至 1.56;p=0.039)和出血并发症(OR:1.80;95%CI:1.11 至 2.90;p=0.016)。在倾向评分匹配分析中,ASC PCI 与主要结局无关联(OR:1.23;95%CI:0.94 至 1.60;p=0.124),但与出血并发症的增加显著相关(OR:2.49;95%CI:1.25 至 4.95;p=0.009)。
在 ASC 行 PCI 的商业保险患者进行 FRF 检查的可能性较低,且出血并发症的发生几率高于 HOPD 治疗的患者。随着 Medicare ASC PCI 数量的增加,有必要进行进一步的研究。