Eshrati Babak, Mokhayeri Hamid, Rokni Mohammad Bagher, Kheirandish Farnaz, Mafi Moharam, Mokhayeri Ali, Kayedi Mohammad Hassan
Preventive Medicine & Public Health Research Center, Iran University of Medical Sciences, Tehran, Iran.
Department of Communicable Disease Control and Prevention, Deputy of Health, Lorestan University of Medical Sciences, Khorramabad, Iran.
J Parasit Dis. 2020 Dec;44(4):806-812. doi: 10.1007/s12639-020-01255-z. Epub 2020 Aug 1.
According to previous studies in Lorestan Province, western Iran on human fascioliasis, we aimed to understand the epidemiology of the disease and to identify the cases in rural and nomad regions of this province. The studied population was a rural and nomadic population of nine districts of Lorestan province, of which 1053 were selected according to the population of each studied county based on random sampling in 2016-2017. Initially, a questionnaire was completed for each person, including age, gender, education, occupation, use of local native aquatic plants and history of travel to the northern provinces of the country where fasciolosis has been reported mostly. Then, 5 ml blood samples were taken and the samples were evaluated as for anti- specific antibodies using ELISA technique. Overall, 1053 individuals were participated, of which 28 (2.66%) were infected with fasciolosis and 18 positive cases were female. The highest infection rate was in the age group of 20-29 years (23%) followed by 30-39 years of age (22%). There was no significant difference between the rate of infection in terms of gender ( = 0.89), age (= 0.15), travel history to the northern provinces of the country (= 0.089), history of aquatic plant consumption called Balmak natively (= 0.48), history of surface water consumption (springs, streams) (= 0.18), and occupation (= 0.43). Considering the results of current and previous studies it seems that the disease in the Lorestan province is expanding and new foci in different parts of the province are formed or are being formed. Therefore, the preventive measures, control and treatment should be taken in areas with parasites transmission.
根据此前在伊朗西部洛雷斯坦省开展的关于人体片形吸虫病的研究，我们旨在了解该病的流行病学情况，并识别该省农村和游牧地区的病例。研究人群为洛雷斯坦省9个区的农村和游牧人口，2016 - 2017年根据每个研究县的人口数量通过随机抽样选取了1053人。首先，为每个人填写一份问卷，内容包括年龄、性别、教育程度、职业、当地本土水生植物的食用情况以及前往该国北部省份的旅行史，该国北部省份是片形吸虫病报告最多的地区。然后，采集5毫升血液样本，使用酶联免疫吸附测定技术评估样本中的抗特异性抗体。总体而言，1053人参与了研究，其中28人（2.66%）感染了片形吸虫病，18例阳性病例为女性。感染率最高的年龄组为20 - 29岁（23%），其次是30 - 39岁（22%）。在性别（P = 0.89）、年龄（P = 0.15）、前往该国北部省份的旅行史（P = 0.089）、食用当地称为巴尔马克的水生植物的历史（P = 0.48）、饮用地表水（泉水、溪流）的历史（P = 0.18）以及职业（P = 0.43）方面，感染率没有显著差异。考虑到当前和以往研究的结果，洛雷斯坦省的该病似乎正在蔓延，该省不同地区正在形成或正在出现新的疫源地。因此，应在寄生虫传播地区采取预防、控制和治疗措施。
