[重庆市江津区小学生感染情况的患病率及危险因素]

[Prevalence and risk factors of infections among primary school students in Jiangjin District, Chongqing City].

作者信息

Ning C Q, Kang J M, Li Y T, Chen H H, Chu Y H, Yu Y F, Wu X P, Ai L, Chen J X, Tian L G, Liao Q D

机构信息

National Institute of Parasitic Disease, Chinese Center for Disease Control and Prevention, Chinese Center for Tropical Disease Research, WHO Collaborating Center for Tropical Diseases, National Center for International Research on Tropical Diseases, Ministry of Science and Technology, Key Laboratory of Parasites and Vector Biology, National Health Commission, Shanghai 200025, China.

Jiangjin District Center for Disease Control and Prevention, Chongqing City, China.

出版信息

Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi. 2020 Oct 20;32(5):489-497. doi: 10.16250/j.32.1374.2020189.

DOI:10.16250/j.32.1374.2020189

PMID:33185060

Abstract

OBJECTIVE

To investigate the prevalence and risk factors of infections among primary school students in Jiangjin District, Chongqing City.

METHODS

A cross-sectional questionnaire survey was conducted among students sampled from a primary school in Jiangjin District, Chongqing City on April, 2018, and their stool samples were collected for microscopic examinations, culture and PCR assays to analyze the prevalence of infections and subtype of the parasite. In addition, the risk factors of infections among primary school students were identified using univariate analysis and multivariate logistic regression analysis.

RESULTS

A total of 466 primary students were surveyed, and the subjects had a mean age of (9.81±1.66) years and included 236 males (50.64%) and 230 females (49.36%). The prevalence of infections was 15.24% (71/466) among the study students, and there was no significance difference in the prevalence between male and fe- male students (16.52% vs. 13.91%; 2 = 0.616, = 0.433). In addition, there was a significant difference in the prevalence of infections among grade 1 (6.35%, 4/63), grade 2 (5.17%, 3/58), grade 3 (21.74%, 15/69), grade 4 (25.30%, 21/83), grade 5 (10.19%, 11/108) and grade 6 students (20.00%, 17/85) (2 = 15.410, = 0.009). There were four subtypes characterized (ST1, ST3, ST6 and ST7), in which ST6 was the most common subtype (45.07%, 32/71), followed by ST3 (25.35%, 18/71). Multivariate logistic regression analysis revealed that minority ethnicity [odds ratio () = 4.259, 95% confidential inter- val () : (1.161, 15.621)] and low maternal education level (primary school and below) [ = 9.038, 95% : (1.125, 72.642)] were identified as risk factors of infection among primary school students in Jiangjin District, Chongqing City.

CONCLUSIONS

There is a high prevalence of infections detected among primary school students in Jiangjin District, Chongqing City, and ST6 and ST3 are predominant subtypes. Minority ethnicity and low maternal education level (primary school and below) are risk factors for infections in primary school students.

摘要

目的

调查重庆市江津区小学生寄生虫感染的患病率及危险因素。

方法

2018年4月对从重庆市江津区一所小学抽取的学生进行横断面问卷调查，并采集其粪便样本进行显微镜检查、培养及聚合酶链反应（PCR）检测，以分析寄生虫感染的患病率及寄生虫亚型。此外，采用单因素分析和多因素logistic回归分析确定小学生寄生虫感染的危险因素。

结果

共调查466名小学生，受试者平均年龄为（9.81±1.66）岁，其中男生236名（50.64%），女生230名（49.36%）。研究学生中寄生虫感染的患病率为15.24%（71/466），男女生患病率差异无统计学意义（16.52%对13.91%；χ² = 0.616，P = 0.433）。此外，一年级（6.35%，4/63）、二年级（5.17%，3/58）、三年级（21.74%，15/69）、四年级（25.30%，21/83）、五年级（10.19%，11/108）和六年级学生（20.00%，17/85）的寄生虫感染患病率差异有统计学意义（χ² = 15.410，P = 0.009）。共鉴定出4种寄生虫亚型（ST1、ST3、ST6和ST7），其中ST6是最常见的亚型（45.07%，32/71），其次是ST3（25.35%，18/71）。多因素logistic回归分析显示，少数民族[比值比（OR） = 4.259，95%置信区间（CI）：（1.161，15.621）]和母亲低教育水平（小学及以下）[OR = 9.038，95%CI：（1.125，72.642）]被确定为重庆市江津区小学生寄生虫感染的危险因素。